The cancer is over, now what?: Understanding risk, changing outcomes Journal Article


Authors: Oeffinger, K. C.; Tonorezos, E. S.
Article Title: The cancer is over, now what?: Understanding risk, changing outcomes
Abstract: About 26,000 adolescents and young adults ages 15 to 29 years are diagnosed with invasive cancer each year. Although >80% will survive beyond 5 years from their cancer diagnosis, many will develop serious morbidity or die prematurely secondary to health problems in part related to their cancer therapy. This article provides a brief overview of mortality, morbidity, and health status among long-term survivors of adolescent and young adult (AYA) cancer. Four examples were used to illustrate the potential of risk-reducing strategies: breast cancer after chest irradiation, coronary artery disease after chest irradiation, cardiovascular disease in testicular cancer survivors, and the multitude of health problems faced by survivors receiving an allogeneic hematopoietic stem cell transplant. A conceptual model for risk-based health care was presented and future directions of the delivery of care for AYA cancer survivors discussed. Copyright © 2011 American Cancer Society.
Keywords: cancer survival; review; cisplatin; solid tumor; cancer radiotherapy; radiation dose; outcome assessment; breast cancer; morbidity; cancer therapy; cancer mortality; survivor; late effects; cancer survivor; risk assessment; health status; cardiovascular disease; allogeneic hematopoietic stem cell transplantation; physical activity; high risk population; risk reduction; testis cancer; coronary artery disease; health care delivery; functional disease; adolescents; risk-based healthcare; young adults
Journal Title: Cancer
Volume: 117
Issue: Suppl. 10
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 2011-05-15
Start Page: 2250
End Page: 2257
Language: English
DOI: 10.1002/cncr.26051
PROVIDER: scopus
PUBMED: 21523742
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 23 June 2011" - "CODEN: CANCA" - "Source: Scopus"
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  1. Kevin Oeffinger
    296 Oeffinger