Strategies to improve outcomes of autologous hematopoietic cell transplant in lymphoma Review

  


Authors: Dahi, P. B.; Lazarus, H. M.; Sauter, C. S.; Giralt, S. A.
Review Title: Strategies to improve outcomes of autologous hematopoietic cell transplant in lymphoma
Abstract: High-dose chemotherapy and autologous hematopoietic cell transplantation (HDT-AHCT) remains an effective therapy in lymphoma. Over the past several decades, HDT with BEAM (carmustine, etoposide, cytarabine, and melphalan) and CBV (cyclophosphamide, carmustine, and etoposide) have been the most frequently used preparatory regimens for AHCT in Hodgkin (HL) and non-Hodgkin lymphoma (NHL). This article reviews alternative combination conditioning regimens, as well as novel transplant strategies that have been developed, to reduce transplant-related toxicity while maintaining or improving efficacy. These data demonstrate that incorporation of maintenance therapy posttransplant might be the best way to improve outcomes. © 2018, Springer Nature Limited.
Journal Title: Bone Marrow Transplantation
Volume: 54
Issue: 7
ISSN: 0268-3369
Publisher: Nature Publishing Group  
Date Published: 2019-07-01
Start Page: 943
End Page: 960
Language: English
DOI: 10.1038/s41409-018-0378-z
PUBMED: 30390059
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055992758&doi=10.1038%2fs41409-018-0378-z&partnerID=40&md5=09b1b8ec5401dea2514c661444fbfeaf
Notes: Review -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Sergio Andres Giralt
    1050 Giralt
  2. Craig Steven Sauter
    334 Sauter
  3. Parastoo Bahrami Dahi
    294 Dahi
Related MSK Work