In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1 Journal Article
| Authors: | Gress, T.; Baldini, A.; Rocchi, M.; Furneaux, H.; Posner, J. B.; Siniscalco, M. |
| Article Title: | In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1 |
| Abstract: | A cDNA clone encoding the major antigen (CDR62) associated with the antibody-induced paraneoplastic cerebellar degeneration has been used to identify the chromosomal location of the corresponding structural gene(s) by screening for its retention in a panel of rodent-human somatic cell hybrids. Having established the synteny of the gene with the autosome 16, we proceeded to its precise subregional mapping by in situ fluorescence hybridization with a recombinant lambda phage containing the genomic region homologous to the cDNA gene. The latter studies pin-pointed the chromosomal localization of the structural CDR62 gene within the interval 16p12-16p13.1. © 1992. |
| Keywords: | dna binding protein; dna-binding proteins; fluorescence; in situ hybridization; gene mapping; dna; rodentia; nucleic acid hybridization; chromosome mapping; chromosome 16p; chromosomes, human, pair 16; leucine zipper protein; restriction mapping; hybrid cell; chromosome banding; cerebellum degeneration; human; article; leucine zippers; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; genes, structural |
| Journal Title: | Genomics |
| Volume: | 13 |
| Issue: | 4 |
| ISSN: | 0888-7543 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1992-08-01 |
| Start Page: | 1340 |
| End Page: | 1342 |
| Language: | English |
| DOI: | 10.1016/0888-7543(92)90063-x |
| PUBMED: | 1505970 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |
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