Advances in experimental and translational research in the treatment of hepatocellular carcinoma Journal Article

   


Authors: Kidner, T.; Dai, M.; Adusumilli, P. S.; Fong, Y.
Article Title: Advances in experimental and translational research in the treatment of hepatocellular carcinoma
Abstract: Hepatocellular cancer (HCC) is the fifth-leading cause of cancer and the third-leading cause of cancer related deaths world-wide. Current treatment options are limited, as HCC has been shown to be a highly resistant type of cancer to most current treatment modalities. Novel approaches are being explored in the fields of gene therapy, viral oncolytics, radioembolization, and several new biologic therapies. This article summarizes these recent clinical findings and discusses what role they will have in the future treatment of HCC. © 2008 Elsevier Inc. All rights reserved.
Keywords: platelet derived growth factor; somatomedin; vasculotropin; unclassified drug; review; doxorubicin; erlotinib; fluorouracil; cancer growth; cancer risk; chemoembolization; liver cell carcinoma; carcinoma, hepatocellular; liver neoplasms; cancer radiotherapy; evidence-based medicine; incidence; carcinoembryonic antigen; epidermal growth factor receptor; interleukin 8; risk factors; protein tyrosine kinase; angiogenesis; cancer research; cancer therapy; carcinogenesis; scatter factor; tumor suppressor gene; enzyme phosphorylation; immunotherapy; gene therapy; oncolytic virotherapy; thymidine kinase; biological therapy; cryoablation; radiofrequency ablation; electrosurgery; herpes simplex virus; ganciclovir; vaccine; drug delivery system; fibroblast growth factor; measles virus; prodrug; onyx 015; cytosine deaminase; flucytosine; adenovirus; nitric oxide; microwave therapy; microsphere; yttrium 90; vesicular stomatitis virus; radioembolization; edmonton vaccine strain; purine nucleoside phosphorylase; microwave coagulation therapy
Journal Title: Surgical Oncology Clinics of North America
Volume: 17
Issue: 2
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2008-01-01
Start Page: 377
End Page: 389
Language: English
DOI: 10.1016/j.soc.2008.01.002
PUBMED: 18375358
PROVIDER: scopus
PMCID: PMC3269813
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-41049105819&partnerID=40&md5=cbaa7f1722328042822b3cf12af3be37
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: SOCAF" - "Source: Scopus"
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MSK Authors
  1. Travis Kidner
    1 Kidner
  2. Menghua Dai
    4 Dai
  3. Yuman Fong
    775 Fong
  4. Prasad S Adusumilli
    496 Adusumilli
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