Treatment sequencing for simultaneous colorectal liver metastases Review


Authors: Krell, R. W.; D'Angelica, M. I.
Review Title: Treatment sequencing for simultaneous colorectal liver metastases
Abstract: Up to 25% of patients with colorectal cancer present with simultaneous metastases and the liver is frequently the only metastatic site. This review will review treatment sequence planning considerations—including metastatic burden, primary tumor site, chemotherapy response, and ability to perform minimally invasive surgery—for patients with simultaneous resectable colorectal liver metastases. In addition, this review will address conversion chemotherapy, combined vs staged surgeries, and their possible sequences. © 2019 Wiley Periodicals, Inc.
Keywords: multimodality cancer therapy; antineoplastic agents; liver neoplasms; combined modality therapy; antineoplastic agent; neoplasm recurrence, local; pathology; colorectal neoplasms; colorectal tumor; tumor recurrence; liver tumor; neoplasm metastasis; surgery; liver resection; minimally invasive surgery; hepatectomy; parenchyma; secondary; procedures; minimally invasive surgical procedures; humans; human; conversion chemotherapy; parenchymal tissue
Journal Title: Journal of Surgical Oncology
Volume: 119
Issue: 5
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2019-04-01
Start Page: 583
End Page: 593
Language: English
DOI: 10.1002/jso.25424
PUBMED: 30816577
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 May 2019 -- Source: Scopus
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  1. Robert Wallace Krell
    5 Krell