Surgical therapy of liver metastases Journal Article
| Authors: | Kuvshinoff, B.; Fong, Y. |
| Article Title: | Surgical therapy of liver metastases |
| Abstract: | The liver is the most common site of metastatic disease from both gastrointestinal and extra-intestinal malignancies. Historically, only a minority of patients with colorectal liver metastases were candidates for resection. However, over the past several decades, liver resection has evolved as a safe and potentially curative treatment for hepatic colorectal metastases. The development of active chemotherapy and molecular targeted therapies, together with newer modalities like radiofrequency ablation, have expanded the indications for hepatic resection and improved survival. Selected patients with isolated liver metastases from neuroendocrine tumors, germ cell cancers, ocular melanoma, gastrointestinal stromal tumors (GIST), and breast cancer also may be considered for hepatic surgery. © 2007 Elsevier Inc. All rights reserved. |
| Keywords: | cancer survival; cancer surgery; surgical technique; clinical trial; bevacizumab; fluorouracil; cancer combination chemotherapy; chemoembolization; patient selection; liver neoplasms; neoadjuvant therapy; colorectal cancer; gastrointestinal stromal tumor; melanoma; controlled clinical trial; multiple cycle treatment; ovary cancer; breast cancer; randomized controlled trial; antineoplastic combined chemotherapy protocols; dexamethasone; cetuximab; kidney carcinoma; irinotecan; neuroendocrine tumor; colorectal neoplasms; gastrointestinal neoplasms; liver metastasis; systematic review; folinic acid; chemotherapy, cancer, regional perfusion; liver resection; choroid melanoma; hepatectomy; oxaliplatin; radiofrequency ablation; testis cancer; floxuridine; germ cell tumor; meta analysis; catheter ablation; fatty liver; carcinoma, neuroendocrine; vein occlusion; pirarubicin |
| Journal Title: | Seminars in Oncology |
| Volume: | 34 |
| Issue: | 3 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2007-06-01 |
| Start Page: | 177 |
| End Page: | 185 |
| Language: | English |
| DOI: | 10.1053/j.seminoncol.2007.03.003 |
| PUBMED: | 17560979 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 16" - "Export Date: 17 November 2011" - "CODEN: SOLGA" - "Source: Scopus" |
