"BFA bodies": A subcompartment of the endoplasmic reticulum Journal Article


Authors: Orci, L.; Perrelet, A.; Ravazzola, M.; Wieland, F. T.; Schekman, R.; Rothman, J. E.
Article Title: "BFA bodies": A subcompartment of the endoplasmic reticulum
Abstract: A specialized region of the endoplasmic reticulum - the BFA body - is defined by the site of accumulation of coatomer when nonclathrin coat protein (COP)-coated vesicle assembly is prevented by the drug brefeldin A (BFA). BFA bodies are formed by part smooth, part rough domains of endoplasmic reticulum that are cis to the classical transitional endoplasmic reticulum and to BFA-induced Golgi remnants.
Keywords: immunohistochemistry; nonhuman; animal cell; animal; microscopy, electron; animal tissue; protein assembly; membrane proteins; animalia; endoplasmic reticulum; rat; rats; structure analysis; protein determination; cell organelle; golgi complex; antibody labeling; microtubule-associated proteins; intracellular membranes; coatomer protein; cell ultrastructure; pancreas islet; cyclopentanes; islets of langerhans; golgi apparatus; coat protein; golgi; coatomer; priority journal; article; brefeldin a; support, non-u.s. gov't; brefeldin; sec23p
Journal Title: Proceedings of the National Academy of Sciences of the United States of America
Volume: 90
Issue: 23
ISSN: 0027-8424
Publisher: National Academy of Sciences  
Date Published: 1993-12-01
Start Page: 11089
End Page: 11093
Language: English
DOI: 10.1073/pnas.90.23.11089
PUBMED: 8248213
PROVIDER: scopus
PMCID: PMC47927
DOI/URL:
Notes: Article -- Export Date: 1 March 2019 -- Source: Scopus
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  1. James E Rothman
    120 Rothman