Neurotransmission: Harnessing fusion machinery at the synapse Journal Article


Authors: Söllner, T.; Rothman, J. E.
Article Title: Neurotransmission: Harnessing fusion machinery at the synapse
Abstract: Neurotransmission requires the docking of synaptic vesicles to the presynaptic plasma membrane, and their signal-dependent fusion. These processes use a general 'machinery' operating at several intracellular vesicular transport steps and, in addition, use a set of unique components that characterizes this specific form of regulated secretion. This review summarizes recent progress that has significantly increased our understanding of how intracellular transport vesicles dock and fuse with their target membrane, both in the synapse and elsewhere. © 1994.
Keywords: review; nonhuman; animal; animal tissue; nerve tissue proteins; membrane proteins; exocytosis; synapse; intracellular membranes; neurotransmission; synaptic transmission; synaptic vesicles; synapse vesicle; human; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title: Trends in Neurosciences
Volume: 17
Issue: 8
ISSN: 0166-2236
Publisher: Elsevier Science, Inc.  
Date Published: 1994-08-01
Start Page: 344
End Page: 348
Language: English
DOI: 10.1016/0166-2236(94)90178-3
PUBMED: 7526506
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 February 2019 -- Source: Scopus
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  1. Thomas H Sollner
    65 Sollner
  2. James E Rothman
    120 Rothman