Mechanisms of intracellular protein transport Journal Article
| Author: | Rothman, J. E. |
| Article Title: | Mechanisms of intracellular protein transport |
| Abstract: | Recent advances have uncovered the general protein apparatus used by all eukaryotes for intracellular transport, including secretion and endocytosis, and for triggered exocytosis of hormones and neurotransmitters. Membranes are shaped into vesicles by cytoplasmic coats which then dissociate upon GTP hydrolysis. Both vesicles and their acceptor membranes carry targeting proteins which interact specifically to initiate docking. A general apparatus then assembles at the docking site and fuses the vesicle with its target. © 2002 Nature Publishing Group. |
| Keywords: | review; proteins; animal; protein targeting; intracellular transport; eukaryota; protein transport; protein secretion; endocytosis; biological transport; exocytosis; organelles; golgi complex; coated vesicle; membrane fusion; coated vesicles; golgi apparatus; priority journal |
| Journal Title: | Nature |
| Volume: | 372 |
| Issue: | 6501 |
| ISSN: | 0028-0836 |
| Publisher: | Nature Publishing Group |
| Date Published: | 1994-11-03 |
| Start Page: | 55 |
| End Page: | 63 |
| Language: | English |
| DOI: | 10.1038/372055a0 |
| PUBMED: | 7969419 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
