Authors: | Söllner, T. H.; Rothman, J. E. |
Article Title: | Molecular machinery mediating vesicle budding, docking and fusion |
Abstract: | A general machinery buds and fuses transport vesicles which connect intracellular compartments with each other and allow communication with the extracellular environment. Cytoplasmic coat proteins deform membranes to bud vesicles and interact directly or indirectly with cargo molecules. Compartment-specific SNAREs (SNAP receptors) on vesicles and target membranes dock vesicles and provide a scaffolding for the general fusion machinery to initiate lipid bilayer fusion. |
Keywords: | models, biological; membrane proteins; short survey; lipid bilayers; lipid bilayer; capsid; membrane vesicle; vesicular transport proteins; membrane biology; membrane fusion; eukaryotic cells; coated vesicles; membrane receptor; cytoplasm protein; arf; snare proteins; synaptic vesicles; snare; coat proteins; nsf; snap; n ethylmaleimide; cargo receptor; vesicle budding and fusion |
Journal Title: | Experientia |
Volume: | 52 |
Issue: | 12 |
ISSN: | 0014-4754 |
Publisher: | Birkhaeuser Science |
Date Published: | 1996-12-01 |
Start Page: | 1021 |
End Page: | 1025 |
Language: | English |
DOI: | 10.1007/bf01952097 |
PUBMED: | 8988241 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Short Survey -- Export Date: 23 May 2018 -- Source: Scopus |