Molecular machinery mediating vesicle budding, docking and fusion Journal Article


Authors: Söllner, T. H.; Rothman, J. E.
Article Title: Molecular machinery mediating vesicle budding, docking and fusion
Abstract: A general machinery buds and fuses transport vesicles which connect intracellular compartments with each other and allow communication with the extracellular environment. Cytoplasmic coat proteins deform membranes to bud vesicles and interact directly or indirectly with cargo molecules. Compartment-specific SNAREs (SNAP receptors) on vesicles and target membranes dock vesicles and provide a scaffolding for the general fusion machinery to initiate lipid bilayer fusion.
Keywords: models, biological; membrane proteins; short survey; lipid bilayers; lipid bilayer; capsid; membrane vesicle; vesicular transport proteins; membrane biology; membrane fusion; eukaryotic cells; coated vesicles; membrane receptor; cytoplasm protein; arf; snare proteins; synaptic vesicles; snare; coat proteins; nsf; snap; n ethylmaleimide; cargo receptor; vesicle budding and fusion
Journal Title: Experientia
Volume: 52
Issue: 12
ISSN: 0014-4754
Publisher: Birkhaeuser Science  
Date Published: 1996-12-01
Start Page: 1021
End Page: 1025
Language: English
DOI: 10.1007/bf01952097
PUBMED: 8988241
PROVIDER: scopus
DOI/URL:
Notes: Short Survey -- Export Date: 23 May 2018 -- Source: Scopus
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  1. Thomas H Sollner
    65 Sollner
  2. James E Rothman
    120 Rothman