Implications of the SNARE hypothesis for intracellular membrane topology and dynamics Journal Article


Authors: Rothman, J. E.; Warren, G.
Article Title: Implications of the SNARE hypothesis for intracellular membrane topology and dynamics
Abstract: The SNARE hypothesis provides a mechanism for the specific docking and fusion of transport vesicles with their target membranes. A simple extension of the hypothesis can explain many cellular processes, including the stacking of Golgi cisternae, retrograde transport and homotypic fusion; it can also explain the morphology of intracellular membranes and their dynamics during mitosis. © 1994 Elsevier Science Ltd. All rights reserved.
Keywords: carrier protein; review; mitosis; animal; biological model; models, biological; nerve tissue proteins; gtp-binding proteins; membrane proteins; physiology; animalia; carrier proteins; membrane protein; guanine nucleotide binding protein; nerve protein; ultrastructure; golgi complex; intracellular membranes; membrane fusion; golgi apparatus; intracellular membrane; synaptobrevin; support, non-u.s. gov't; soluble n ethylmaleimide sensitive factor attachment protein; soluble n-ethylmaleimide-sensitive factor attachment protein; gtp binding proteins; vesicle-associated membrane protein
Journal Title: Current Biology
Volume: 4
Issue: 3
ISSN: 0960-9822
Publisher: Cell Press  
Date Published: 1994-03-01
Start Page: 220
End Page: 233
Language: English
DOI: 10.1016/s0960-9822(00)00051-8
PROVIDER: scopus
PUBMED: 7922327
DOI/URL:
Notes: Export Date: 14 January 2019 -- Article -- Source: Scopus
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  1. James E Rothman
    120 Rothman