Author: | Portenoy, R. K. |
Article Title: | Management of common opioid side effects during long-term therapy of cancer pain |
Abstract: | For most patients with cancer pain, the primary goal of opioid pharmacotherapy is a satisfactory balance between analgesia and side effects. Consequently, the assessment and treatment of opioid side effects is a fundamental aspect of therapy, which may increase the likelihood of a favourable treatment outcome, potentially allow higher and more efficacious opioid doses, and improve quality of life by reducing other uncomfortable symptoms. This review describes the presentation, assessment and management of adverse neuropsychological acid gastrointestinal effects due to opioid drugs. These common side effects pose the major challenge for the clinician who undertakes the long-term opioid therapy of patients with cancer pain. |
Keywords: | constipation; review; neurotoxicity; neoplasms; unindexed drug; pain; gastrointestinal symptom; nausea; vomiting; methylphenidate; opiate; delirium; cancer pain; neuroleptic agent; antiemetic agent; corticosteroid; cognition disorders; metoclopramide; macrogol; atropine; naloxone; antihistaminic agent; oral drug administration; benzodiazepine; psychostimulant agent; mood disorders; dexamphetamine; pemoline; lactulose; docusate sodium; laxative; sorbitol; cholinergic receptor blocking agent; domperidone; cisapride; bisacodyl; sodium dihydrogen phosphate; scopolamine; meclozine; narcotics; magnesium hydroxide; human; narcotic analgesics; phenolphthalein; magnesium citrate; senna |
Journal Title: | Annals of the Academy of Medicine, Singapore |
Volume: | 23 |
Issue: | 2 |
ISSN: | 0304-4602 |
Publisher: | Academy Of Medicine Singapore |
Date Published: | 1994-03-01 |
Start Page: | 160 |
End Page: | 170 |
Language: | English |
PUBMED: | 8080221 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Export Date: 1 February 2019 -- Source: Scopus |