The management of cancer pain Journal Article
| Authors: | Cherny, N. I.; Portenoy, R. K. |
| Article Title: | The management of cancer pain |
| Abstract: | Surveys indicate that clinicians are frequently ill equipped to treatcancer pain. Pain is often poorly assessed, and many caregivers lacksufficient knowledge to optimize treatment. Effective management requiresan understanding of pain pathophysiology, the ability to identify andevaluate pain syndromes, and familiarity with proven therapeuticstrategies. Opioid pharmacotherapy is the mainstay of treatment. Practicalaspects of opioid therapy include selection of both drug and route, dosetitration, and management of side effects. Specific strategies for themanagement of patients who are unable to attain an acceptable balancebetween pain relief and side effects include both noninvasive interventions (such as adjuvant analgesics, psychological therapies, and physiatrictechniques) and invasive interventions (such as the use of intraspinalopioids, neural blockade, and neuroablative therapies). Sedation is anoption at the end of life for the treatment of pain that is refractory toother interventions. These approaches can provide adequate relief to thevast majority of patients, most of whom will respond to systemicpharmacotherapy alone. Patients with refractory pain should have access tospecialists in pain management or palliative medicine. Copyright © 1994 American Cancer Society |
| Keywords: | review; pathophysiology; neoplasm; neoplasms; unindexed drug; pain; opiate; palliative therapy; sedation; cancer pain; pethidine; acetylsalicylic acid; paracetamol; diclofenac; ibuprofen; naproxen; salsalate; sulindac; morphine; analgesics; decision making; hydromorphone; ketorolac; analgesia; analgesic agent; oxycodone; codeine; hydrocodone; pentazocine; buprenorphine; dextropropoxyphene; nalbuphine; flurbiprofen; ketoprofen; dihydrocodeine; butorphanol; cancer; human; priority journal; choline magnesium trisalicylate; fenoprofen; oxaprozin; dezocine |
| Journal Title: | CA - A Cancer Journal for Clinicians |
| Volume: | 44 |
| Issue: | 5 |
| ISSN: | 0007-9235 |
| Publisher: | Wiley-Blackwell |
| Date Published: | 1994-09-01 |
| Start Page: | 262 |
| End Page: | 303 |
| Language: | English |
| DOI: | 10.3322/canjclin.44.5.263 |
| PROVIDER: | scopus |
| PUBMED: | 8076244 |
| DOI/URL: | |
| Notes: | Export Date: 14 January 2019 -- Article -- Source: Scopus |
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