Misconceptions and controversies regarding the use of opioids in cancer pain Conference Paper


Author: Foley, K. M.
Title: Misconceptions and controversies regarding the use of opioids in cancer pain
Conference Title: Janssen Satellite Symposium at the 7th World Congress on Pain
Abstract: The WHO has created a Cancer Pain Relief Programme and developed guidelines for the treatment of cancer pain. Implementation of the analgesic guidelines, assurance of drug availability (specifically opioids), education of health-care professionals, and designating cancer pain as a priority for all national cancer control programmes are the major goals. Recent studies of medical students, physicians, nurses and state medical boards demonstrate a significant lack of knowledge with regard to the theoretical and practical understanding of the use of analgesic drugs, particularly opioids, in the management of cancer pain. Communication between physicians and patients about pain symptoms has also been shown to be problematic. Limited availability of opioids, their excessive regulation, and the lack of use of alternatives to systemic analgesics also prevent adequate management. Although analgesic drug therapy is the mainstay of treatment, opioid use remains a controversial issue. Some of the controversies include their role in the management of neuropathic pain, which has been suggested to be 'opioid-resistant', as well as the choice of opioid drug. A third controversy is the route of administration. The impetus for the development of novel routes has come from the goals of maximising analgesia, minimising side effects, and providing convenient dosing schedules for patients who require parenteral administration. Other important controversial issues are the development of tolerance and the relationship of pain management to patient requests for physician-assisted suicide and euthanasia.
Keywords: conference paper; neurotoxicity; neoplasms; pain; opiate; cancer pain; practice guideline; pethidine; suicide; world health organization; seizure; methadone; morphine; analgesics, opioid; hydromorphone; analgesia; drug tolerance; intravenous drug administration; analgesic agent; fentanyl; levorphanol; oxycodone; oral drug administration; intramuscular drug administration; drug choice; hypersensitivity; euthanasia; subcutaneous drug administration; intracerebroventricular drug administration; vocational education; human; priority journal; intrathecal drug administration; transdermal drug administration; rectal drug administration
Journal Title Anti-Cancer Drugs
Volume: 6
Issue: Suppl. 3
Conference Dates: 1993 August
Conference Location: Paris, France
ISBN: 0959-4973
Publisher: Lippincott Williams & Wilkins  
Date Published: 1995-04-01
Start Page: 4
End Page: 13
Language: English
PUBMED: 7606036
PROVIDER: scopus
DOI: 10.1097/00001813-199504003-00002
DOI/URL:
Notes: Conference Paper -- Export Date: 28 August 2018 -- Source: Scopus
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  1. Kathleen M Foley
    199 Foley