Stereotaxic 14-gauge breast biopsy: How many core biopsy specimens are needed? Journal Article


Authors: Liberman, L.; Dershaw, D. D.; Rosen, P. P.; Abramson, A. F.; Deutch, B. M.; Hann, L. E.
Article Title: Stereotaxic 14-gauge breast biopsy: How many core biopsy specimens are needed?
Abstract: PURPOSE: To determine the optimum number of specimens to obtain at stereotaxic core breast biopsy. MATERIALS AND METHODS: Stereotaxic biopsies were performed in 145 mammographically evident lesions by using a dedicated table with patients in the prone position. Samples were obtained with an automated gun and a 14-gauge needle. Indications for biopsy were calcifications (n = 53) and masses (n = 92). Three to 11 (mean, 5.4) core biopsy specimens were obtained per lesion and were analyzed separately. RESULTS: Diagnostic material was obtained in the first specimen in 102 (70%) of the 145 lesions. Obtaining two, three, four, five, and six core specimens yielded a diagnosis in 117 (81%), 129 (89%), 132 (91%), 137 (94%), and 140 (97%) of the 145 lesions, respectively. Obtaining five specimens yielded a diagnosis in 46 (87%) of the 53 calcifications and 91 (99%) of the 92 masses. Obtaining six specimens resulted in a diagnosis in 49 (92%) lesions evident as calcifications but did not improve the yield on masses. CONCLUSION: Stereotaxic 14-gauge core biopsy achieved a 99% diagnostic yield with five specimens for masses. Additional specimens may be necessary to diagnose some calcified lesions.
Keywords: major clinical study; histopathology; cancer diagnosis; breast cancer; breast; biopsy; mammography; needle; breast biopsy; breast lesion; stereotaxic surgery; breast calcification; human; priority journal; article
Journal Title: Radiology
Volume: 192
Issue: 3
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1994-09-01
Start Page: 793
End Page: 795
Language: English
DOI: 10.1148/radiology.192.3.8058949
PROVIDER: scopus
PUBMED: 8058949
DOI/URL:
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MSK Authors
  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Lucy E Hann
    69 Hann
  4. Paul P Rosen
    201 Rosen
  5. Beth M. Deutch
    10 Deutch