Radiography of microcalcifications in stereotaxic mammary core biopsy specimens Journal Article


Authors: Liberman, L.; Evans, W. P. 3rd; Dershaw, D. D.; Hann, L. E.; Deutch, B. M.; Abramson, A. F.; Rosen, P. P.
Article Title: Radiography of microcalcifications in stereotaxic mammary core biopsy specimens
Abstract: PURPOSE: To describe the technique of specimen radiography in stereotaxically guided core biopsies and evaluate its role in detection and diagnosis of microcalcifications in breast tissue. MATERIALS AND METHODS: Specimens from 361 stereotaxic breast core biopsies of 72 nonpalpable lesions with mammographic evidence of microcalcifications were obtained from 65 patients. Specimens were placed in saline on microscope slides and radiographed. RESULTS: Microcalcifications were detected radiographically in 146 of 361 (40%) cores. If calcifications were present on specimen radiographs, histologic detection of these calcifications was made in 114 of 146 (78%) specimens, and diagnosis was made in 118 of 146 (81%). If calcifications were not present on specimen radiographs, histologic detection was obtained in 27 of 215 (13%) specimens and specific diagnosis in 81 of 215 (38%). CONCLUSION: Specimen radiography should be routinely performed in stereotaxic core biopsies of breast microcalcifications to ensure appropriate tissue has been obtained and to direct pathologic diagnosis of the tissue specimens.
Keywords: adult; human tissue; major clinical study; histopathology; breast; mammography; biopsy, needle; radiography; technique; breast biopsy; in vitro; breast diseases; stereotaxic surgery; calcinosis; middle age; breast calcification; stereotaxic techniques; breast radiography; human; female; priority journal; article; breast, biopsy; breast, calcification; specimen radiography
Journal Title: Radiology
Volume: 190
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1994-01-01
Start Page: 223
End Page: 225
Language: English
PROVIDER: scopus
PUBMED: 8259409
DOI: 10.1148/radiology.190.1.8259409
DOI/URL:
Notes: RADIOLOGY -- Cited By :159 -- Export Date: 14 January 2019 -- Article -- CODEN: RADLA C2 - 8259409 -- Source: Scopus
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MSK Authors
  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Lucy E Hann
    69 Hann
  4. Paul P Rosen
    201 Rosen
  5. Beth M. Deutch
    10 Deutch