Guidelines of care for the management of primary cutaneous melanoma Journal Article


Authors: Bichakjian, C. K.; Halpern, A. C.; Johnson, T. M.; Foote Hood, A.; Grichnik, J. M.; Swetter, S. M.; Tsao, H.; Barbosa, V. H.; Chuang, T. Y.; Duvic, M.; Ho, V. C.; Sober, A. J.; Beutner, K. R.; Bhushan, R.; Smith Begolka, W.
Article Title: Guidelines of care for the management of primary cutaneous melanoma
Abstract: The incidence of primary cutaneous melanoma has been increasing dramatically for several decades. Melanoma accounts for the majority of skin cancer-related deaths, but treatment is nearly always curative with early detection of disease. In this update of the guidelines of care, we will discuss the treatment of patients with primary cutaneous melanoma. We will discuss biopsy techniques of a lesion clinically suspicious for melanoma and offer recommendations for the histopathologic interpretation of cutaneous melanoma. We will offer recommendations for the use of laboratory and imaging tests in the initial workup of patients with newly diagnosed melanoma and for follow-up of asymptomatic patients. With regard to treatment of primary cutaneous melanoma, we will provide recommendations for surgical margins and briefly discuss nonsurgical treatments. Finally, we will discuss the value and limitations of sentinel lymph node biopsy and offer recommendations for its use in patients with primary cutaneous melanoma. © 2010 by the American Academy of Dermatology, Inc.
Keywords: cancer survival; cancer surgery; histopathology; cancer localization; cancer recurrence; cancer growth; cancer risk; treatment planning; antineoplastic agents; cancer radiotherapy; cancer staging; positron emission tomography; follow up; follow-up studies; lymph node dissection; lymphatic metastasis; neoplasm staging; lymphoscintigraphy; sentinel lymph node biopsy; evidence based medicine; evidence-based medicine; mitosis; melanoma; computer assisted tomography; imiquimod; skin neoplasms; malignant lentigo; hutchinson's melanotic freckle; practice guideline; tumor biopsy; diagnostic imaging; biopsy; epiluminescence microscopy; distant metastasis; age; nail disease; postoperative complication; cancer invasion; health care cost; hyperplasia; cancer size; micrometastasis; cancer relapse; lactate dehydrogenase; lymphocyte; false positive result; chemosurgery; lactate dehydrogenase blood level; cryosurgery; satellitosis; adipose tissue; follow-up; cryotherapy; repeat procedure; surgical margins; aminoquinolines; pathology report; nail diseases; off label drug use; melanocytic hyperplasia; neurotropism; neoplasm grading; asymptomatic diseases
Journal Title: Journal of the American Academy of Dermatology
Volume: 65
Issue: 5
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2011-01-01
Start Page: 1032
End Page: 1047
Language: English
DOI: 10.1016/j.jaad.2011.04.031
PROVIDER: scopus
PUBMED: 21868127
DOI/URL:
Notes: --- - "Export Date: 2 November 2011" - "CODEN: JAADD" - "Source: Scopus"
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  1. Allan C Halpern
    396 Halpern