Clinical and histological efficacy of a secretion of the mollusk Cryptomphalus aspersa in the treatment of cutaneous photoaging Journal Article

  


Authors: Tribo-Boixareu, M. J.; Parrado-Romero, C.; Rais, B.; Reyes, E.; Vitale-Villarejo, M. A.; Gonzalez, S.
Article Title: Clinical and histological efficacy of a secretion of the mollusk Cryptomphalus aspersa in the treatment of cutaneous photoaging
Abstract: In this article, the authors describe the efficacy of a natural secretion of Cryptomphalus aspersa (SCA) in cutaneous photoaging.This placebo-free, open-label study comprised 15 women exhibiting facial photoaging.Treatment with SCA for 3 months induced a significant reduction in photoaging on the Glogau scale. Silicone replica analysis showed significant improvements in skin roughness and wrinkle depth. Histopathological analysis revealed a marked improvement in both dermal and epidermal architecture, as well as epidermal proliferation and the percentage of cutaneous area covered by microvessels. In summary, treatment with SCA for 3 months resulted in a significant improvement of the clinical and histological signs of photoaging, and these correlated with both subjective and objective assessments of chronic photodamage.
Journal Title: Cosmetic Dermatology
Volume: 22
Issue: 5
ISSN: 1041-3766
Publisher: Frontline Medical Communications, Inc.  
Date Published: 2009-05-01
Start Page: 247
End Page: 252
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-80053381727&partnerID=40&md5=1733cb84d2b108dcd655a351d3c3dbea
Notes: --- - "Export Date: 2 November 2011" - "CODEN: CDOEB" - "Source: Scopus"