Retrospective analysis of posaconazole suspension dosing strategies in a pediatric oncology population: Single-center experience Journal Article


Authors: Mathew, S.; Kussin, M. L.; Liu, D.; Pozotrigo, M.; Seyboth, B.; Thackray, J.; Yan, S. Q.; Hsu, M.; Cohen, N.; Seo, S. K.
Article Title: Retrospective analysis of posaconazole suspension dosing strategies in a pediatric oncology population: Single-center experience
Abstract: Limited data on optimal posaconazole dosing strategies for pediatric patients exist. In this study, we found that the median initial dose in patients who achieved a posaconazole plasma concentration of 0.7 μg/mL was 22.8 mg/kg per day whereas the median initial dose in those who did not reach the target concentration was 15.8 mg/kg per day; this result suggests that higher initial doses might be warranted. © The Author 2017. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved.
Keywords: oncology; posaconazole; pediatrics
Journal Title: Journal of the Pediatric Infectious Diseases Society
Volume: 6
Issue: 3
ISSN: 2048-7193
Publisher: Oxford University Press  
Date Published: 2017-09-01
Start Page: e149
End Page: e151
Language: English
DOI: 10.1093/jpids/pix058
PROVIDER: scopus
PUBMED: 28903522
PMCID: PMC5907872
DOI/URL:
Notes: Article -- Export Date: 2 November 2017 -- Source: Scopus
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MSK Authors
  1. Meier Hsu
    102 Hsu
  2. Susan Seo
    59 Seo
  3. Sherry Mathew
    11 Mathew
  4. Qiong   Yan
    6 Yan
  5. Dazhi   Liu
    8 Liu
  6. Michelle Lynn Kussin
    1 Kussin