Retrospective analysis of posaconazole suspension dosing strategies in a pediatric oncology population: Single-center experience Journal Article

   


Authors: Mathew, S.; Kussin, M. L.; Liu, D.; Pozotrigo, M.; Seyboth, B.; Thackray, J.; Yan, S. Q.; Hsu, M.; Cohen, N.; Seo, S. K.
Article Title: Retrospective analysis of posaconazole suspension dosing strategies in a pediatric oncology population: Single-center experience
Abstract: Limited data on optimal posaconazole dosing strategies for pediatric patients exist. In this study, we found that the median initial dose in patients who achieved a posaconazole plasma concentration of 0.7 μg/mL was 22.8 mg/kg per day whereas the median initial dose in those who did not reach the target concentration was 15.8 mg/kg per day; this result suggests that higher initial doses might be warranted. © The Author 2017. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved.
Keywords: oncology; posaconazole; pediatrics
Journal Title: Journal of the Pediatric Infectious Diseases Society
Volume: 6
Issue: 3
ISSN: 2048-7193
Publisher: Oxford University Press  
Date Published: 2017-09-01
Start Page: e149
End Page: e151
Language: English
DOI: 10.1093/jpids/pix058
PROVIDER: scopus
PUBMED: 28903522
PMCID: PMC5907872
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85031765431&doi=10.1093%2fjpids%2fpix058&partnerID=40&md5=c26dbf0bfc98bb134cf352a5da89cc11
Notes: Article -- Export Date: 2 November 2017 -- Source: Scopus
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MSK Authors
  1. Meier Hsu
    169 Hsu
  2. Susan Seo
    122 Seo
  3. Melissa Pozotrigo
    11 Pozotrigo
  4. Sherry Mathew
    19 Mathew
  5. Nina Cohen Orsini
    32 Cohen Orsini
  6. Brian Michael Seyboth
    11 Seyboth
  7. Jennifer Linda Thackray
    17 Thackray
  8. Qiong Yan
    10 Yan
  9. Dazhi Liu
    45 Liu
  10. Michelle Lynn Kussin
    2 Kussin
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