Adjuvant therapy for rectal cancer: Results and controversies Journal Article
| Author: | Minsky, B. D. |
| Article Title: | Adjuvant therapy for rectal cancer: Results and controversies |
| Abstract: | During the past decade, advances have been made in the adjuvant treatment of resectable rectal cancer. Postoperative combined-modality therapy significantly improves local control and survival. Recent Intergroup postoperative trials have focused on the identification of optimal chemotherapeutic agents and their method of administration. Preoperative therapy has the potential advantages of producing less acute toxicity and increasing the likelihood of sphincter preservation. New chemotherapeutic agents and radiation techniques are active areas of investigation. |
| Keywords: | cancer survival; treatment outcome; survival rate; clinical trial; review; cisplatin; fluorouracil; diarrhea; multimodality cancer therapy; antineoplastic agents; cancer adjuvant therapy; cancer radiotherapy; postoperative care; preoperative care; combined modality therapy; cancer staging; neoplasm staging; blood toxicity; drug effect; irinotecan; vincristine sulfate; randomized controlled trials; folinic acid; drug infusion; mitomycin c; preoperative treatment; oxaliplatin; rectal neoplasms; rectum cancer; anus sphincter; raltitrexed; levamisole; uft; semustine; humans; human; trimetrexate glucuronate |
| Journal Title: | Oncology (Norwalk) |
| Volume: | 12 |
| Issue: | 8 |
| ISSN: | 0890-9091 |
| Publisher: | C M P Medica LLC * The Oncology Group |
| Date Published: | 1998-08-01 |
| Start Page: | 1129 |
| End Page: | 1139 |
| Language: | English |
| PUBMED: | 11236307 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 12 December 2016 -- Source: Scopus |
