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Yanlong Kang

Formats
  1. Journal Article (14)
  2. Meeting Abstract (8)
Groups
  1. Center for Hematologic Malignancies (22)
  2. GSK Faculty (22)
  3. Hematologic Malignancies Research (22)
  4. Molecular Pharmacology and Chemistry Program Faculty (22)
  5. Sloan Kettering Institute Faculty (22)
  6. Sloan Kettering Institute Postdocs (18)

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People
  1. Gabriela Chiosis (22)
  2. Tony Taldone (16)
  3. Anna Rodina Balingcongan (14)
  4. Cristina Clement (8)
  5. Hardik Patel (8)
  6. Alexander Gozman (7)

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Years
  1. 2023 (1)
  2. 2017 (1)
  3. 2015 (2)
  4. 2014 (3)
  5. 2013 (1)
  6. 2012 (2)

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Publications
  1. Cancer Research (5)
  2. Bioorganic & Medicinal Chemistry Letters (3)
  3. Journal of Medicinal Chemistry (3)
  4. ACS Chemical Biology (1)
  5. Abstracts of Papers of the American Chemical Society (1)
  6. Assay and Drug Development Technologies (1)

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Publishers
  1. American Association for Cancer Research (5)
  2. American Chemical Society (5)
  3. Pergamon-Elsevier Science Ltd (4)
  4. Nature Publishing Group (2)
  5. American Society of Hematology (1)
  6. Elsevier Inc. (1)

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Results (22)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • YK5, a small molecule inhibitor of Hsp70 and Hsc70, reveals a multifaceted role for the Hsp70 chaperones in regulating oncogenic and non-oncogenic addiction of tumors
    Meeting Abstract

    Rodina, A.; Kang, Y.; Taldone, T.; Patel, H.; Patel, P.; Caldas-Lopes, E.; Erdjument-Bromage, H.; Guzman, M.; Young, J. C.; Melnick, A.; more...
    Cancer Research (2011)

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  • HSP70 inhibitor, YK5, ablates blast, progenitor and stem cell populations in primary acute myelogenous leukemia cells
    Meeting Abstract

    Rico, J. F.; Sharma, K. K.; Kang, Y. L.; Taldone, T.; Patel, H.; Brennan, S.; Zong, H. L.; Becker, M. W.; Roboz, G. J.; Chiosis, G.; more...
    Blood (2011)

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  • YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
    Meeting Abstract

    Taldone, Tony; Kang, Yanlong; Rodina, Anna; Maharaj, Ronnie; Gozman, Alexander; Cerchietti, Leandro; Wong, Michael J. H.; Baaklini, Imad; Caldas Lopes, Eloisi; Patel, Hardik J.; more...
    Abstracts of Papers of the American Chemical Society (2011)

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  • Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators
    Journal Article

    Ahn, J. H.; Luo, W.; Kim, J.; Rodina, A.; Clement, C. C.; Aguirre, J.; Sun, W.; Kang, Y.; Maharaj, R.; Moulick, K.; more...
    Assay and Drug Development Technologies (2011)

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  • YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells
    Meeting Abstract

    Rodina, A.; Kang, Y.; Maharaj, R.; Gozman, A.; Taldone, T.; Cerchietti, L.; Wong, M. J. H.; Baaklini, I.; Caldas-Lopes, E.; Clement, C. C.; more...
    Cancer Research (2010)

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  • A facile and efficient synthesis of d6-labeled PU-H71, a purine-scaffold Hsp90 inhibitor
    Journal Article

    Taldone, T.; Zatorska, D.; Kang, Y.; Chiosis, G.
    Journal of Labelled Compounds and Radiopharmaceuticals (2010)

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  • Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines
    Journal Article

    Tao, H.; Kang, Y.; Taldone, T.; Chiosis, G.
    Bioorganic & Medicinal Chemistry Letters (2009)

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  • Design of a fluorescence polarization assay platform for the study of human Hsp70
    Journal Article

    Kang, Y.; Taldone, T.; Clement, C. C.; Fewell, S. W.; Aguirre, J.; Brodsky, J. L.; Chiosis, G.
    Bioorganic & Medicinal Chemistry Letters (2008)

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  • Discovery and development of purine-scaffold Hsp90 inhibitors
    Journal Article

    Chiosis, G.; Kang, Y.; Sun, W.
    Expert Opinion on Drug Discovery (2008)

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  • Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
    Journal Article

    Rodina, A.; Vilenchik, M.; Moulick, K.; Aguirre, J.; Kim, J.; Chiang, A.; Litz, J.; Clement, C. C.; Kang, Y.; She, Y.; more...
    Nature Chemical Biology (2007)

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