Synapse - Yehuda Goldgur

Results (42)

Pharmacological restoration of GTP hydrolysis by mutant RAS

Journal Article

Cuevas-Navarro, A.; Pourfarjam, Y.; Hu, F.; Rodriguez, D. J.; Vides, A.; Sang, B.; Fan, S.; Goldgur, Y.; de Stanchina, E.; Lito, P.
Nature (2025)

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Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells

Journal Article

Saha, N.; Lee, S. G.; Brockmann, E. C.; de la Cruz, M. J.; Goldgur, Y.; Mendoza, R. P.; de Stanchina, E.; Love, T. M.; Marvald, J.; Xu, Y.; more...
Biomedicine and Pharmacotherapy (2024)

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Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody

Journal Article

Gupta, A.; Kao, K. S.; Yamin, R.; Oren, D. A.; Goldgur, Y.; Du, J.; Lollar, P.; Sundberg, E. J.; Ravetch, J. V.
Nature Communications (2023)

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Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells

Journal Article

Saha, N.; Baek, D. S.; Mendoza, R. P.; Robev, D.; Xu, Y.; Goldgur, Y.; De La Cruz, M. J.; de Stanchina, E.; Janes, P. W.; Xu, K.; more...
Biomedicine and Pharmacotherapy (2023)

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Structures of fission yeast inositol pyrophosphate kinase Asp1 in ligand-free, substrate-bound, and product-bound states

Journal Article

Benjamin, B.; Goldgur, Y.; Jork, N.; Jessen, H. J.; Schwer, B.; Shuman, S.
mBio (2022)

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Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase

Journal Article

Unciuleac, M. C.; Ghosh, S.; de la Cruz, M. J.; Goldgur, Y.; Shuman, S.
RNA (2021)

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Structure of 3-PO(4)/5-OH RNA ligase RtcB in complex with a 5-OH oligonucleotide

Journal Article

Banerjee, A.; Goldgur, Y.; Shuman, S.
RNA (2021)

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Structure of the EphB6 receptor ectodomain

Journal Article

Mason, E. O.; Goldgur, Y.; Robev, D.; Freywald, A.; Nikolov, D. B.; Himanen, J. P.
PLoS ONE (2021)

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Caveat mutator: Alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation

Journal Article

Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2020)

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Mycobacterial DNA polymerase I: Activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme

Journal Article

Ghosh, S.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2020)

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