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Alan H Shih

  1. "Cancer Cell"
Formats
  1. Journal Article (8)
Groups
  1. Adult Leukemia (8)
  2. Center for Hematologic Malignancies (8)
  3. Center for Molecular Imaging and Biotechnology (CMIB) (8)
  4. Department of Medicine (8)
  5. Executive Committee, Center for Hematologic Malignancies (8)
  6. GSK Faculty (8)

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People
  1. Ross Levine (8)
  2. Franck Rapaport (3)
  3. Jay Patel (3)
  4. Kaitlyn Shank (3)
  5. Martin Tallman (3)
  6. Omar Abdel-Wahab (3)

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Years
  1. 2018 (1)
  2. 2016 (1)
  3. 2015 (2)
  4. 2012 (2)
  5. 2011 (1)
  6. 2010 (1)
Publications
  1. Cancer Cell (8)
Publishers
  1. Cell Press (8)

Results (8)

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  • Cooperative epigenetic remodeling by TET2 loss and NRAS mutation drives myeloid transformation and MEK inhibitor sensitivity
    Journal Article

    Kunimoto, H.; Meydan, C.; Nazir, A.; Whitfield, J.; Shank, K.; Rapaport, F.; Maher, R.; Pronier, E.; Meyer, S. C.; Garrett-Bakelman, F. E.; more...
    Cancer Cell (2018)

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  • Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2
    Journal Article

    Inoue, S.; Li, W. Y.; Tseng, A.; Beerman, I.; Elia, A. J.; Bendall, S. C.; Lemonnier, F.; Kron, K. J.; Cescon, D. W.; Hao, Z.; more...
    Cancer Cell (2016)

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  • CHZ868, a type II JAK2 inhibitor, reverses type I JAK inhibitor persistence and demonstrates efficacy in myeloproliferative neoplasms
    Journal Article

    Meyer, S.; Keller, M.; Chiu, S.; Koppikar, P.; Guryanova, O.; Rapaport, F.; Xu, K.; Manova, K.; Pankov, D.; O'reilly, R.; more...
    Cancer Cell (2015)

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  • Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia
    Journal Article

    Shih, A. H.; Jiang, Y.; Meydan, C.; Shank, K.; Pandey, S.; Barreyro, L.; Antony-Debre, I.; Viale, A.; Socci, N.; Sun, Y.; more...
    Cancer Cell (2015)

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  • IDH1 mutations disrupt blood, brain, and barriers
    Journal Article

    Shih, A. H.; Levine, R. L.
    Cancer Cell (2012)

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  • ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
    Journal Article

    Abdel-Wahab, O.; Adli, M.; LaFave, L.; Gao, J.; Hricik, T.; Shih, A.; Pandey, S.; Patel, J.; Chung, Y.; Koche, R.; more...
    Cancer Cell (2012)

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  • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    Journal Article

    Moran-Crusio, K.; Reavie, L.; Shih, A.; Abdel-Wahab, O.; Ndiaye-Lobry, D.; Lobry, C.; Figueroa, M.; Vasanthakumar, A.; Patel, J.; Zhao, X.; more...
    Cancer Cell (2011)

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  • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    Journal Article

    Figueroa, M. E.; Abdel-Wahab, O.; Lu, C.; Ward, P. S.; Patel, J.; Shih, A.; Li, Y.; Bhagwat, N.; Vasanthakumar, A.; Fernandez, H. F.; more...
    Cancer Cell (2010)

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