Synapse - Lawrence Williams

Results (14)

Iterative assembly of glycals and glycal derivatives: The synthesis of glycosylated natural products and complex oligosaccharides

Book Section

Williams, L. J.; Garbaccio, R. M.; Danishefsky, S. J.
In Ernst, B.; Hart, G. W.; Sinay, P. (Eds.) Carbohydrates in Chemistry and Biology (2008)

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Characterization of affinity purified anti-Tn(c) and anti-TF(c) antibodies obtained from prostate cancer patients vaccinated with Tn(c)-KLH or TF(c)-KLH conjugate vaccines

Meeting Abstract

Koide, F.; Ragupathi, G.; Williams, L. J.; Biswas, K.; Slovin, S. F.; Danishefsky, S. J.; Livingston, P. O.
Proceedings of the American Association for Cancer Research Annual Meeting (2002)

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Constructing an adenocarcinoma vaccine: Immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Ley antibodies

Journal Article

Ragupathi, G.; Deshpande, P. P.; Coltart, D. M.; Kim, H. M.; Williams, L. J.; Danishefsky, S. J.; Livingston, P. O.
International Journal of Cancer (2002)

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On the power of chemical synthesis: Immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines

Journal Article

Ragupathi, G.; Coltart, D. M.; Williams, L. J.; Koide, F.; Kagan, E.; Allen, J.; Harris, C.; Glunz, P. W.; Livingston, P. O.; Danishefsky, S. J.
Proceedings of the National Academy of Sciences of the United States of America (2002)

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Principles of mucin architecture: Structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains

Journal Article

Coltart, D. M.; Royyuru, A. K.; Williams, L. J.; Glunz, P. W.; Sames, D.; Kuduk, S. D.; Schwarz, J. B.; Chen, X. T.; Danishefsky, S. J.; Live, D. H.
Journal of the American Chemical Society (2002)

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Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: A phase I trial

Journal Article

Gilewski, T.; Ragupathi, G.; Bhuta, S.; Williams, L. J.; Musselli, C.; Zhang, X. F.; Bencsath, K. P.; Panageas, K. S.; Chin, J.; Hudis, C. A.; more...
Proceedings of the National Academy of Sciences of the United States of America (2001)

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Toward optimized carbohydrate-based anticancer vaccines: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewisy conjugates in mice

Journal Article

Kudryashov, V.; Glunz, P. W.; Williams, L. J.; Hintermann, S.; Danishefsky, S. J.; Lloyd, K. O.
Proceedings of the National Academy of Sciences of the United States of America (2001)

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In pursuit of an anticancer vaccine: A monomolecular construct containing multiple carbohydrate antigens

Journal Article

Williams, L. J.; Harris, C. R.; Glunz, P. W.; Danishefsky, S. J.
Tetrahedron Letters (2000)

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Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: Isolation, quantification, and characterization of immune responses by using totally synthetic immobilized tumor antigens