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Young Park

Formats
  1. Journal Article (9)
  2. Meeting Abstract (6)
  3. Review (1)
Groups
  1. Adult Leukemia (16)
  2. Center for Hematologic Malignancies (16)
  3. Center for Molecular Imaging and Biotechnology (CMIB) (16)
  4. Department of Medicine (16)
  5. Executive Committee, Center for Hematologic Malignancies (16)
  6. GSK Faculty (16)

More Groups

People
  1. Ross Levine (16)
  2. Andrew Dunbar (12)
  3. Richard Koche (7)
  4. Wenbin Xiao (7)
  5. Abdul Karzai (6)
  6. Aishwarya Krishnan (6)

More People

Years
  1. 2024 (4)
  2. 2023 (1)
  3. 2022 (3)
  4. 2021 (2)
  5. 2020 (3)
  6. 2019 (3)
Publications
  1. Blood (8)
  2. Cancer Discovery (3)
  3. Cancer Cell (1)
  4. Cell Reports (1)
  5. Hematology/Oncology Clinics of North America (1)
  6. Journal for ImmunoTherapy of Cancer (1)

More Publications

Publishers
  1. American Society of Hematology (8)
  2. American Association for Cancer Research (3)
  3. Cell Press (2)
  4. American Society for Clinical Investigation (1)
  5. Biomed Central Ltd (1)
  6. Elsevier Inc. (1)

Results (16)

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  • In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy
    Journal Article

    Bowman, R. L.; Dunbar, A. J.; Mishra, T.; Xiao, W.; Waarts, M. R.; Maestre, I. F.; Eisman, S. E.; Cai, L.; Mowla, S.; Shah, N.; more...
    Cancer Cell (2024)

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  • CRISPR dependency screens in primary hematopoietic stem cells identify KDM3B as a genotype-specific vulnerability in IDH2- and TET2-mutant cells
    Journal Article

    Waarts, M. R.; Mowla, S.; Boileau, M.; Martinez Benitez, A. R.; Sango, J.; Bagish, M.; Fernández-Maestre, I.; Shan, Y.; Eisman, S. E.; Park, Y. C.; more...
    Cancer Discovery (2024)

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  • Jak2(V617F) reversible activation shows its essential requirement in myeloproliferative neoplasms
    Journal Article

    Dunbar, A. J.; Bowman, R. L.; Park, Y. C.; O'Connor, K.; Izzo, F.; Myers, R. M.; Karzai, A.; Zaroogian, Z.; Kim, W. J.; Fernandez-Maestre, I.; more...
    Cancer Discovery (2024)

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  • Developing a membrane-proximal CD33-targeting CAR T cell
    Journal Article

    Freeman, R.; Shahid, S.; Khan, A. G.; Mathew, S. C.; Souness, S.; Burns, E. R.; Um, J. S.; Tanaka, K.; Cai, W.; Yoo, S.; more...
    Journal for ImmunoTherapy of Cancer (2024)

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  • CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis
    Journal Article

    Dunbar, A. J.; Kim, D.; Lu, M.; Farina, M.; Bowman, R. L.; Yang, J. L.; Park, Y.; Karzai, A.; Xiao, W.; Zaroogian, Z.; more...
    Blood (2023)

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  • The second generation type II JAK2 inhibitor, AJ1-10502, demonstrates enhanced selectivity, improved therapeutic efficacy and reduced mutant cell fraction compared to type I JAK2 inhibitors in models of myeloproliferative neoplasms (MPNs)
    Meeting Abstract

    Rai, S.; Stetka, J.; Usart, M.; Hao-Shen, H.; Park, Y.; Houston, R.; Martinez Benitez, A. R.; Wereski, M.; Guzzardi, E.; Persaud, S.; more...
    Blood (2022)

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  • JAK2(V617F) reversible activation shows an essential requirement for JAK2(V617F) in myeloproliferative neoplasms (MPNs)
    Meeting Abstract

    Dunbar, A.; Bowman, R. L.; Park, Y.; Izzo, F.; Myers, R. M.; Karzai, A.; Kim, W. J.; Maestre, I. F.; Waarts, M. R.; Nazir, A.; more...
    Blood (2022)

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  • Targeting mutations in cancer
    Journal Article

    Waarts, M. R.; Stonestrom, A. J.; Park, Y. C.; Levine, R. L.
    Journal of Clinical Investigation (2022)

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  • Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors
    Journal Article

    Dunbar, A.; Bolton, K. L.; Devlin, S. M.; Sanchez-Vega, F.; Gao, J.; Mones, J. V.; Wills, J.; Kelly, D.; Farina, M.; Cordner, K. B.; more...
    Blood (2021)

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  • Epigenetic dysregulation of myeloproliferative neoplasms
    Review

    Dunbar, A.; Park, Y.; Levine, R.
    Hematology/Oncology Clinics of North America (2021)

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