The second generation type II JAK2 inhibitor, AJ1-10502, demonstrates enhanced selectivity, improved therapeutic efficacy and reduced mutant cell fraction compared to type I JAK2 inhibitors in models of myeloproliferative neoplasms (MPNs) Meeting Abstract


Authors: Rai, S.; Stetka, J.; Usart, M.; Hao-Shen, H.; Park, Y.; Houston, R.; Martinez Benitez, A. R.; Wereski, M.; Guzzardi, E.; Persaud, S.; Ramzan, H.; Futran, A.; Xu, C.; Greenwood, J.; Mondal, S.; Masse, C.; Levine, R. L.; Skoda, R. C.; Dunbar, A.
Abstract Title: The second generation type II JAK2 inhibitor, AJ1-10502, demonstrates enhanced selectivity, improved therapeutic efficacy and reduced mutant cell fraction compared to type I JAK2 inhibitors in models of myeloproliferative neoplasms (MPNs)
Meeting Title: 64th Annual Meeting of the American Society of Hematology (ASH)
Journal Title: Blood
Volume: 140
Issue: Suppl. 1
Meeting Dates: 2022 Dec 10-13
Meeting Location: New Orleans, LA
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2022-11-15
Start Page: 6722
End Page: 6723
Language: English
ACCESSION: WOS:000893223206328
DOI: 10.1182/blood-2022-162621
PROVIDER: wos
Notes: Meeting Abstract -- Source: Wos
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