Synapse - Colleen Maher

Results (16)

Characterizing the immune effects of enfortumab vedotin (EV) on peripheral blood mononuclear cells (PBMCs) in metastatic urothelial cancer patients (mUC)

Meeting Abstract

Gupta, A.; Sevilla, C.; Pihlstrom, N. L.; Liang, S.; Regazzi, A. M.; McCoy, A. S.; Maher, C. A.; Wong, P.; Ahmed, F.; Funt, S. A.; more...
Journal of Clinical Oncology (2025)

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Quantitatively defined stromal B cell aggregates are associated with response to checkpoint inhibitors in unresectable melanoma

Journal Article

Smithy, J. W.; Peng, X.; Ehrich, F. D.; Moy, A. P.; Yosofvand, M.; Maher, C.; Aleynick, N.; Vanguri, R.; Zhuang, M.; Lee, J.; more...
Cell Reports (2025)

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Correlation of peripheral blood monocytic myeloid-derived suppressor cells (M-MDSC) and T-cell receptor (TCR) dynamics with clinical outcomes in patients (pts) with metastatic urothelial carcinoma (mUC) treated with nivolumab (NIVO)

Meeting Abstract

Gupta, A.; Whiting, K.; Keegan, N. M.; Schmalz, J.; Al-Ahmadie, H. A.; Regazzi, A. M.; McCoy, A. S.; Maher, C. A.; Iyer, G.; Rosenberg, J. E.; more...
Journal of Clinical Oncology (2024)

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Early on-treatment assessment of T cells, cytokines, and tumor DNA with adaptively dosed nivolumab + ipilimumab: Final results from the phase 2 ADAPT-IT study

Journal Article

Smithy, J. W.; Kalvin, H. L.; Ehrich, F. D.; Shah, R.; Adamow, M.; Raber, V.; Maher, C. A.; Kleman, J.; McIntyre, D. A. G.; Shoushtari, A. N.; more...
Clinical Cancer Research (2024)

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Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

Journal Article

Widman, A. J.; Shah, M.; Frydendahl, A.; Halmos, D.; Khamnei, C. C.; Øgaard, N.; Rajagopalan, S.; Arora, A.; Deshpande, A.; Hooper, W. F.; more...
Nature Medicine (2024)

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Integration of peripheral blood- and tissue-based biomarkers of response to immune checkpoint blockade in urothelial carcinoma

Journal Article

Vanguri, R. S.; Smithy, J. W.; Li, Y.; Zhuang, M.; Maher, C. A.; Aleynick, N.; Peng, X.; Al-Ahmadie, H.; Funt, S. A.; Rosenberg, J. E.; more...
Journal of Pathology (2023)

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A topic modeling approach reveals the dynamic T cell composition of peripheral blood during cancer immunotherapy

Journal Article

Peng, X.; Lee, J.; Adamow, M.; Maher, C.; Postow, M. A.; Callahan, M. K.; Panageas, K. S.; Shen, R.
Cell Reports Methods (2023)

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Final clinical results and first translational correlates of a phase 2 trial of adaptively dosed nivolumab and ipilimumab based on early radiographic assessment in advanced melanoma (ADAPT-IT)