Synapse - Renier Brentjens

Results (130)

Virus specific T-lymphocytes genetically modified to target the CD19 antigen eradicates systemic lymphoma in mice

Meeting Abstract

Curran, K. J.; Taylor, C.; Doubrovina, E.; Wang, X.; O'Reilly, R. J.; Sadelain, M.; Kernan, N. A.; Brentjens, R. J.; Riviere, I.
Blood (2010)

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Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo

Journal Article

Na, I. K.; Markley, J. C.; Tsai, J. J.; Yim, N. L.; Beattie, B. J.; Klose, A. D.; Holland, A. M.; Ghosh, A.; Rao, U. K.; Stephan, M. T.; more...
Blood (2010)

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Treatment of chronic lymphocytic leukemia with genetically targeted autologous t cells: Case report of an unforeseen adverse event in a phase i clinical trial

Journal Article

Brentjens, R.; Yeh, R.; Bernal, Y.; Riviere, I.; Sadelain, M.
Molecular Therapy (2010)

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Enhanced in vivo activation of adoptively transferred genetically targeted T cells following cyclophosphamide chemotherapy: Initial results from a phase I clinical trial treating CLL patients with autologous CD19-targeted T cells

Meeting Abstract

Brentjens, R. J.; Hollyman, D.; Park, J.; Santos, E.; Yeh, R.; Stefanski, J.; Taylor, C.; Weiss, M. A.; Filippa, D.; Riviere, I.; more...
Blood (2009)

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Concurrent visualization of trafficking and NFAT signalling in primary T lymphocytes and T cell precursors in vivo

Meeting Abstract

Na, I. K.; Markley, J.; Tsai, J.; Yim, N. L.; Beattie, B. J.; Klose, A. D.; Holland, A. M.; Ghosh, A.; Rao, U. K.; Stephan, M.; more...
Blood (2009)

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Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase

Journal Article

Santos, E. B.; Yeh, R.; Lee, J.; Nikhamin, Y.; Punzalan, B.; Perle, K. L.; Larson, S. M.; Sadelain, M.; Brentjens, R. J.
Nature Medicine (2009)

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The promise and potential pitfalls of chimeric antigen receptors

Journal Article

Sadelain, M.; Brentjens, R.; Riviere, I.
Current Opinion in Immunology (2009)

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Retroviral transduction of murine primary T lymphocytes

Journal Article

Lee, J.; Sadelain, M.; Brentjens, R.
Methods in Molecular Biology (2009)

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Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: Molecular remissions predict for durable complete responses