Treatment of chronic lymphocytic leukemia with genetically targeted autologous t cells: Case report of an unforeseen adverse event in a phase i clinical trial Journal Article

   

Authors:	Brentjens, R.; Yeh, R.; Bernal, Y.; Riviere, I.; Sadelain, M.
Article Title:	Treatment of chronic lymphocytic leukemia with genetically targeted autologous t cells: Case report of an unforeseen adverse event in a phase i clinical trial
Keywords:	cancer chemotherapy; human tissue; aged; fludarabine; clinical trial; disease course; anamnesis; case report; rituximab; drug megadose; letter; t lymphocyte; t-lymphocytes; protein blood level; gene targeting; multiple cycle treatment; cyclophosphamide; cancer resistance; hypotension; cytokine; lymphocyte activation; recombinant fusion proteins; mitoxantrone; ciprofloxacin; phase 1 clinical trial; autopsy; clinical trials, phase i as topic; fatal outcome; chronic lymphatic leukemia; lymphadenopathy; immunotherapy, adoptive; lymphocyte antigen receptor; antigens, cd19; leukemia, lymphocytic, chronic, b-cell; antigens, cd28; lymphocyte count; pentostatin; piperacillin plus tazobactam; tumor cell destruction; allopurinol; leukapheresis; lymphocyte transfusion
Journal Title:	Molecular Therapy
Volume:	18
Issue:	4
ISSN:	1525-0016
Publisher:	Nature Publishing Group
Date Published:	2010-04-01
Start Page:	666
End Page:	668
Language:	English
DOI:	10.1038/mt.2010.31
PUBMED:	20357779
PROVIDER:	scopus
PMCID:	PMC2862525
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-77950480974&partnerID=40&md5=cc6c14c12a7e657fb4899fcd48ee290a
Notes:	--- - "Cited By (since 1996): 16" - "Export Date: 20 April 2011" - "CODEN: MTOHC" - "Source: Scopus"

https://synapse.mskcc.org/synapse/works/has_related_data_chk/3750