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Palak Panchal

Formats
  1. Journal Article (14)
  2. Meeting Abstract (2)
Groups
  1. Center for Hematologic Malignancies (16)
  2. GSK Faculty (16)
  3. Hematologic Malignancies Research (16)
  4. Molecular Pharmacology and Chemistry Program Faculty (16)
  5. Sloan Kettering Institute Faculty (16)
  6. Sloan Kettering Institute Postdocs (16)

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People
  1. Gabriela Chiosis (16)
  2. Sahil Sharma (12)
  3. Anna Rodina Balingcongan (10)
  4. Chander Digwal (10)
  5. Pengrong Yan (8)
  6. Suhasini Joshi (8)

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Years
  1. 2024 (2)
  2. 2023 (4)
  3. 2022 (1)
  4. 2021 (3)
  5. 2020 (2)
  6. 2019 (2)

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Publications
  1. Nature Communications (4)
  2. Biomedicines (2)
  3. Blood (1)
  4. Cell Reports (1)
  5. Chaperones: Methods and Protocols. 2nd ed (1)
  6. Clinical Lymphoma, Myeloma and Leukemia (1)

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Publishers
  1. Nature Publishing Group (5)
  2. Cell Press (3)
  3. MDPI (2)
  4. Springer Nature (2)
  5. American Society of Hematology (1)
  6. Elsevier Inc. (1)

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Results (16)

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  • Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation
    Journal Article

    Roychowdhury, T.; McNutt, S. W.; Pasala, C.; Nguyen, H. T.; Thornton, D. T.; Sharma, S.; Botticelli, L.; Digwal, C. S.; Joshi, S.; Yang, N.; more...
    Nature Communications (2024)

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  • Synthesis and characterization of click chemical probes for single-cell resolution detection of epichaperomes in neurodegenerative disorders
    Journal Article

    Bay, S.; Digwal, C. S.; Rodilla Martín, A. M.; Sharma, S.; Stanisavljevic, A.; Rodina, A.; Attaran, A.; Roychowdhury, T.; Parikh, K.; Toth, E.; more...
    Biomedicines (2024)

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  • Unraveling the mechanism of epichaperome modulation by zelavespib: Biochemical insights on target occupancy and extended residence time at the site of action
    Journal Article

    Sharma, S.; Joshi, S.; Kalidindi, T.; Digwal, C. S.; Panchal, P.; Lee, S. G.; Zanzonico, P.; Pillarsetty, N.; Chiosis, G.
    Biomedicines (2023)

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  • How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view
    Journal Article

    Castelli, M.; Yan, P.; Rodina, A.; Digwal, C. S.; Panchal, P.; Chiosis, G.; Moroni, E.; Colombo, G.
    Structure (2023)

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  • Use of native-PAGE for the identification of epichaperomes in cell lines
    Journal Article

    Roychowdhury, T.; Santhaseela, A. R.; Sharma, S.; Panchal, P.; Rodina, A.; Chiosis, G.; Calderwood, S. K.; Prince, T. L.
    Chaperones: Methods and Protocols. 2nd ed (2023)

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  • Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    Journal Article

    Rodina, A.; Xu, C.; Digwal, C. S.; Joshi, S.; Patel, Y.; Santhaseela, A. R.; Bay, S.; Merugu, S.; Alam, A.; Yan, P.; more...
    Nature Communications (2023)

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  • Synthesis of (124)I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice
    Journal Article

    Sharma, S.; Kalidindi, T.; Joshi, S.; Digwal, C. S.; Panchal, P.; Burnazi, E.; Lee, S. G.; Pillarsetty, N.; Chiosis, G.
    STAR Protocols (2022)

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  • Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
    Journal Article

    Joshi, S.; Gomes, E. D.; Wang, T.; Corben, A.; Taldone, T.; Gandu, S.; Xu, C.; Sharma, S.; Buddaseth, S.; Yan, P.; more...
    Communications Biology (2021)

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  • Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
    Journal Article

    Bolaender, A.; Zatorska, D.; He, H.; Joshi, S.; Sharma, S.; Digwal, C. S.; Patel, H. J.; Sun, W.; Imber, B. S.; Ochiana, S. O.; more...
    Nature Communications (2021)

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  • Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia
    Journal Article

    Sugita, M.; Wilkes, D. C.; Bareja, R.; Eng, K. W.; Nataraj, S.; Jimenez-Flores, R. A.; Yan, L. B.; De Leon, J. P.; Croyle, J. A.; Kaner, J.; more...
    npj Precision Oncology (2021)

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