Synapse - Navin Chintala

Results (27)

CAR T-cell intrinsic PD1 dominant negative receptor (PD1DNR) functions by both cell-intrinsic and extrinsic mechanisms

Meeting Abstract

Amador, A.; Hou, Z.; Chintala, N.; Adusumilli, P. S.
Journal of Immunology (2023)

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Ex vivo pleural effusion cultures to study chimeric antigen receptor T cell cytotoxicity in an immunocompetent environment

Journal Article

Tano, Z. E.; Kiesgen, S.; Chintala, N. K.; Dozier, J.; Quach, H. T.; Messinger, J.; Tan, K. S.; Adusumilli, P. S.
Cell Reports Methods (2023)

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Tumor-targeted nonablative radiation promotes solid tumor CAR T-cell therapy efficacy

Journal Article

Quach, H. T.; Skovgard, M. S.; Villena-Vargas, J.; Bellis, R. Y.; Chintala, N. K.; Amador-Molina, A.; Bai, Y.; Banerjee, S.; Saini, J.; Xiong, Y.; more...
Cancer Immunology Research (2023)

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c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation

Journal Article

Xiong, Y.; Taleb, M.; Misawa, K.; Hou, Z.; Banerjee, S.; Amador-Molina, A.; Jones, D. R.; Chintala, N. K.; Adusumilli, P. S.
Nature Cancer (2023)

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Organ-specific heterogeneity in tumor-infiltrating immune cells and cancer antigen expression in primary and autologous metastatic lung adenocarcinoma

Journal Article

Restle, D.; Dux, J.; Li, X.; Byun, A. J.; Choe, J. K.; Li, Y.; Vaghjiani, R. G.; Thomas, C.; Misawa, K.; Tan, K. S.; more...
Journal for ImmunoTherapy of Cancer (2023)

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Correlative analysis from a phase I clinical trial of intrapleural administration of oncolytic vaccinia virus (Olvi-vec) in patients with malignant pleural mesothelioma

Journal Article

Chintala, N. K.; Choe, J. K.; McGee, E.; Bellis, R.; Saini, J. K.; Banerjee, S.; Moreira, A. L.; Zauderer, M. G.; Adusumilli, P. S.; Rusch, V. W.
Frontiers in Immunology (2023)

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Tumor and tumor-associated macrophage programmed death-ligand 1 expression is associated with adjuvant chemotherapy benefit in lung adenocarcinoma

Journal Article

Gross, D. J.; Chintala, N. K.; Vaghjiani, R. G.; Grosser, R.; Tan, K. S.; Li, X.; Choe, J.; Li, Y.; Aly, R. G.; Emoto, K.; more...
Journal of Thoracic Oncology (2022)

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Promoting functional persistence in solid tumor CAR T-cell therapy: Mesothelin-targeted CAR (M28z1XXPD1DNR) with T-cell intrinsic PD1 dominant negative receptor

Meeting Abstract

Adusumilli, P. S.; Amador, A. M.; Chintala, N.; Hou, Z.; Offin, M.; Pineda, J.; Senechal, B.; Quach, H. T.; Bellis, R.; Banerjee, S.; more...
Annals of Oncology (2021)

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A phase I trial of regional mesothelin-targeted CAR T-cell therapy in patients with malignant pleural disease, in combination with the anti-PD-1 agent pembrolizumab