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Laura Sepp-Lorenzino

Formats
  1. Journal Article (23)
  2. Meeting Abstract (14)
  3. Conference Paper (2)
  4. Book Section (1)
Groups
  1. Sloan Kettering Institute Faculty (37)
  2. Breast Medicine Service (36)
  3. Department of Medicine (36)
  4. GSK Faculty (36)
  5. Molecular Pharmacology and Chemistry Program Faculty (36)
  6. Solid Tumor Oncology Division (36)

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People
  1. Neal Rosen (36)
  2. Samuel Danishefsky (12)
  3. Fuzhong Zheng (8)
  4. David Lebwohl (7)
  5. Mark Moasser (7)
  6. Gabriela Chiosis (5)

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Years
  1. 2001 (3)
  2. 2000 (6)
  3. 1999 (5)
  4. 1998 (6)
  5. 1997 (2)
  6. 1996 (7)

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Publications
  1. Proceedings of the American Association for Cancer Research Annual Meeting (9)
  2. Bioorganic & Medicinal Chemistry Letters (3)
  3. Clinical Cancer Research (3)
  4. Journal of Biological Chemistry (3)
  5. Breast Cancer Research and Treatment (2)
  6. Cancer Research (2)

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Publishers
  1. American Association for Cancer Research (15)
  2. Nature Publishing Group (4)
  3. American Society for Biochemistry and Molecular Biology (3)
  4. Pergamon-Elsevier Science Ltd (3)
  5. Springer (3)
  6. American Chemical Society (2)

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Results (40)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells
    Journal Article

    Chiosis, G.; Timaul, M. N.; Lucas, B.; Munster, P. N.; Zheng, F. F.; Sepp-Lorenzino, L.; Rosen, N.
    Chemistry and Biology (2001)

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  • Farnesyl:protein transferase inhibitors as potential agents for the management of human prostate cancer
    Journal Article

    Sepp-Lorenzino, L.; Tjaden, G.; Moasser, M. M.; Timaul, N.; Ma, Z.; Kohl, N. E.; Gibbs, J. B.; Oliff, A.; Rosen, N.; Scher, H. I.
    Prostate Cancer and Prostatic Diseases (2001)

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  • LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family
    Journal Article

    Chiosis, G.; Rosen, N.; Sepp-Lorenzino, L.
    Bioorganic & Medicinal Chemistry Letters (2001)

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  • Biological therapy
    Book Section

    Rosen, N.; Sepp-Lorenzino, L.; Lippman, M. E.
    In Harris, J. R.; Lippman, M. E.; Morrow, M.; Hellman, S. (Eds.) Diseases of the Breast. 2nd ed (2000)

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  • Development of targeted ansamycins as novel anti-steroid agents and tyrosine kinase inhibitors in the treatment of breast and prostate cancers
    Meeting Abstract

    Zheng, F. F.; Kuduk, S. D.; Munster, P. N.; Chiosis, G.; Sepp-Lorenzino, L.; Danishefsky, S. J.; Rosen, N.
    Clinical Cancer Research (2000)

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  • Design and synthesis of small molecule inhibitors of the Hsp90 chaperone
    Meeting Abstract

    Chiosis, G.; Timaul, M. N.; Sepp-Lorenzino, L.; Zheng, F. Z. F.; Lucas, B.; Danishefsky, S. J.; Rosen, N.
    Clinical Cancer Research (2000)

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  • Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases
    Journal Article

    Zheng, F. F.; Kuduk, S. D.; Chiosis, G.; Mùˆnster, P. N.; Sepp-Lorenzino, L.; Danishefsky, S. J.; Rosen, N.
    Cancer Research (2000)

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  • A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice. Prospects for long-term clinical utility
    Journal Article

    Sirotnak, F. M.; Sepp-Lorenzino, L.; Kohl, N. E.; Rosen, N.; Scher, H. I.
    Cancer Chemotherapy and Pharmacology (2000)

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  • Synthesis and evaluation of geldanamycin-testosterone hybrids
    Journal Article

    Kuduk, S. D.; Harris, C. R.; Zheng, F. F.; Sepp-Lorenzino, L.; Ouerfelli, O.; Rosen, N.; Danishefsky, S. J.
    Bioorganic & Medicinal Chemistry Letters (2000)

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  • Farnesyltransferase inhibitor (FTI) and EGF receptor (EGFR) blockade induced a synergistic G(1) arrest in H-Ras-transformed human breast epithelial cells
    Meeting Abstract

    Chou, J. L.; Moasser, M.; Sepp-Lorenzino, L.; Mendelsohn, J.; Norton, L.; Rosen, N.
    Proceedings of the American Association for Cancer Research Annual Meeting (1999)

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