Authors: | Woodruff, J. M.; Antonescu, C. R.; Erlandson, R. A.; Boland, P. J. |
Article Title: | Low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes): Report of a case that metastasized |
Abstract: | 'Hyalinizing spindle cell tumor with giant rosettes' is a tumor recently described by Lane et al. arid thought by them possibly to represent a form of low-grade fibromyxoid sarcoma. Proof of a metastatic potential was lacking. We report an example of this tumor on the arm of a 28-year-old woman. The ultrastructural study of the tumor confirmed the fibroblastic nature of the lesion, which subsequently metastasized to the lung. Histologically, the giant rosettes simulated palisaded granulomas. Our findings warrant classifying the tumor as a sarcoma, and we suggest the designation low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes). |
Keywords: | adult; human tissue; case report; cancer grading; lung neoplasms; lung metastasis; fibrosarcoma; soft tissue sarcoma; rosette formation; spindle cell carcinoma; ultrastructure; soft tissue neoplasms; arm; hyaline degeneration; low-grade fibromyxoid sarcoma; humans; human; female; article; hyalinized spindle cell tumor with giant rosettes; low-grade soft-tissue sarcoma |
Journal Title: | American Journal of Surgical Pathology |
Volume: | 23 |
Issue: | 11 |
ISSN: | 0147-5185 |
Publisher: | Lippincott Williams & Wilkins |
Date Published: | 1999-11-01 |
Start Page: | 1423 |
End Page: | 1428 |
Language: | English |
DOI: | 10.1097/00000478-199911000-00015 |
PUBMED: | 10555013 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 16 August 2016 -- Source: Scopus |