Low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes): Report of a case that metastasized Journal Article


Authors: Woodruff, J. M.; Antonescu, C. R.; Erlandson, R. A.; Boland, P. J.
Article Title: Low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes): Report of a case that metastasized
Abstract: 'Hyalinizing spindle cell tumor with giant rosettes' is a tumor recently described by Lane et al. arid thought by them possibly to represent a form of low-grade fibromyxoid sarcoma. Proof of a metastatic potential was lacking. We report an example of this tumor on the arm of a 28-year-old woman. The ultrastructural study of the tumor confirmed the fibroblastic nature of the lesion, which subsequently metastasized to the lung. Histologically, the giant rosettes simulated palisaded granulomas. Our findings warrant classifying the tumor as a sarcoma, and we suggest the designation low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes).
Keywords: adult; human tissue; case report; cancer grading; lung neoplasms; lung metastasis; fibrosarcoma; soft tissue sarcoma; rosette formation; spindle cell carcinoma; ultrastructure; soft tissue neoplasms; arm; hyaline degeneration; low-grade fibromyxoid sarcoma; humans; human; female; article; hyalinized spindle cell tumor with giant rosettes; low-grade soft-tissue sarcoma
Journal Title: American Journal of Surgical Pathology
Volume: 23
Issue: 11
ISSN: 0147-5185
Publisher: Lippincott Williams & Wilkins  
Date Published: 1999-11-01
Start Page: 1423
End Page: 1428
Language: English
DOI: 10.1097/00000478-199911000-00015
PUBMED: 10555013
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 16 August 2016 -- Source: Scopus
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  1. Patrick J Boland
    160 Boland
  2. Cristina R Antonescu
    895 Antonescu
  3. James M Woodruff
    162 Woodruff
  4. Robert A Erlandson
    125 Erlandson