The 2016 revision of the World Health Organization classification of lymphoid neoplasms Journal Article


Authors: Swerdlow, S. H.; Campo, E.; Pileri, S. A.; Harris, N. L.; Stein, H.; Siebert, R.; Advani, R.; Ghielmini, M.; Salles, G. A.; Zelenetz, A. D.; Jaffe, E. S.
Article Title: The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Abstract: A revision of the nearly 8-year-old World Health Organization classification of the lymphoid neoplasms and the accompanying monograph is being published. It reflects a consensus among hematopathologists, geneticists, and clinicians regarding both updates to current entities as well as the addition of a limited number of new provisional entities. The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies. The major changes are reviewed with an emphasis on the most important advances in our understanding that impact our diagnostic approach, clinical expectations, and therapeutic strategies for the lymphoid neoplasms.
Keywords: t-cell lymphoma; chronic lymphocytic-leukemia; positive; burkitt-lymphoma; paraffin-embedded tissue; gamma-delta-t; predominant hodgkin lymphoma; identifies recurrent mutations; mucocutaneous ulcer; follicular-lymphoma; lymphoproliferative-disorder
Journal Title: Blood
Volume: 127
Issue: 20
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2016-05-20
Start Page: 2375
End Page: 2390
Language: English
ACCESSION: WOS:000378333900008
DOI: 10.1182/blood-2016-01-643569
PROVIDER: wos
PMCID: PMC4874220
PUBMED: 26980727
Notes: Review -- Source: Wos
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  1. Andrew D Zelenetz
    768 Zelenetz