The 5th edition of the World Health Organization classification of mature lymphoid and stromal tumors–An overview and update Review
| Authors: | Attygalle, A. D.; Chan, J. K. C.; Coupland, S. E.; Du, M. Q.; Ferry, J. A.; de Jong, D.; Gratzinger, D.; Lim, M. S.; Naresh, K. N.; Nicolae, A.; Ott, G.; Rosenwald, A.; Schuh, A.; Siebert, R.; on behalf of the wHO 5th edition classification Project |
| Review Title: | The 5th edition of the World Health Organization classification of mature lymphoid and stromal tumors–An overview and update |
| Abstract: | The purpose of this review is to give an overview on the conceptual framework and major developments of the upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid tumours (WHO-HAEM5) and to highlight the most significant changes made in WHO-HAEM5 compared with the revised 4th edition (WHO-HAEM4R) of lymphoid and stromal neoplasms. The changes from the revised 4th edition include the reorganization of entities by means of a hierarchical system that is realized throughout the 5th edition of the WHO classification of tumors of all organ systems, a modification of nomenclature for some entities, the refinement of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities. For the first time, tumor-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms are included in the classification. © 2024 Informa UK Limited, trading as Taylor & Francis Group. |
| Keywords: | review; disease classification; neoplasm; neoplasms; spleen; plasmacytoma; hodgkin disease; b cell lymphoma; cutaneous t cell lymphoma; peripheral t cell lymphoma; t cell lymphoma; immune response; lymph node; lymphoma; stroma; world health organization; nomenclature; disease predisposition; conceptual framework; mesenchyme; anaplastic large cell lymphoma; paraprotein; lymphatic system tumor; humans; human; tfh cell; neoplastic cell transformation; modification of nomenclature; refinement of diagnostic criteria; who-haem5 |
| Journal Title: | Leukemia and Lymphoma |
| Volume: | 65 |
| Issue: | 4 |
| ISSN: | 1042-8194 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2024-01-01 |
| Start Page: | 413 |
| End Page: | 429 |
| Language: | English |
| DOI: | 10.1080/10428194.2023.2297939 |
| PUBMED: | 38189838 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
