Occupational outcomes of adult childhood cancer survivors Journal Article


Authors: Kirchhoff, A. C.; Krull, K. R.; Ness, K. K.; Park, E. R.; Oeffinger, K. C.; Hudson, M. M.; Stovall, M.; Robison, L. L.; Wickizer, T.; Leisenring, W.
Article Title: Occupational outcomes of adult childhood cancer survivors
Abstract: BACKGROUND: The authors examined whether survivors from the Childhood Cancer Survivor Study were less likely to be in higher-skill occupations than a sibling comparison and whether certain survivors were at higher risk for lower-skill jobs. METHODS: The authors created 3 mutually exclusive occupational categories for participants aged ≥25 years: Managerial/Professional, Nonphysical Service/Blue Collar, and Physical Service/Blue Collar. The authors examined currently employed survivors (4845) and their siblings (1727) in multivariable generalized linear models to evaluate the likelihood of being in 1 of the 3 occupational categories. Multinomial logistic regression was used among all participants to examine the likelihood of these outcomes compared to being unemployed (survivors, 6671; siblings, 2129). Multivariable linear models were used to assess survivor occupational differences by cancer- and treatment-related variables. Personal income was compared by occupation. RESULTS: Employed survivors were less often in higher-skilled Managerial/Professional occupations (relative risk, 0.93; 95% confidence interval 0.89-0.98) than their siblings. Survivors who were black, were diagnosed at a younger age, or had high-dose cranial radiation were less likely to hold Managerial/Professional occupations than other survivors. In multinomial models, female survivors' likelihood of being in full-time Managerial/ Professional occupations (27%) was lower than male survivors (42%) and female (41%) and male (50%) siblings. Survivors' personal income was lower than siblings within each of the 3 occupational categories in models adjusted for sociodemographic variables. CONCLUSIONS: Adult childhood cancer survivors are employed in lower-skill jobs than siblings. Survivors with certain treatment histories are at higher risk for lower-skill jobs and may require vocational assistance throughout adulthood. Copyright © 2011 American Cancer Society.
Keywords: adult; controlled study; limb salvage; major clinical study; cancer radiotherapy; neurosurgery; antineoplastic agent; neoplasms; childhood cancer; skull irradiation; late effects; cancer survivor; survivors; occupation; amputation; sex difference; platinum complex; sibling; onset age; socioeconomic factors; income; negro; occupations; employment; unemployment; blue collar worker; manager; manual labor
Journal Title: Cancer
Volume: 117
Issue: 13
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 2011-07-01
Start Page: 3033
End Page: 3044
Language: English
DOI: 10.1002/cncr.25867
PROVIDER: scopus
PUBMED: 21246530
PMCID: PMC3547616
DOI/URL:
Notes: --- - "Export Date: 17 August 2011" - "CODEN: CANCA" - "Source: Scopus"
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  1. Kevin Oeffinger
    296 Oeffinger