Unemployment among adult survivors of childhood cancer: A report from the childhood cancer survivor study Journal Article


Authors: Kirchhoff, A. C.; Leisenring, W.; Krull, K. R.; Ness, K. K.; Friedman, D. L.; Armstrong, G. T.; Stovall, M.; Park, E. R.; Oeffinger, K. C.; Hudson, M. M.; Robison, L. L.; Wickizer, T.
Article Title: Unemployment among adult survivors of childhood cancer: A report from the childhood cancer survivor study
Abstract: Background: Adult childhood cancer survivors report high levels of unemployment, although it is unknown whether this is because of health or employability limitations. Objectives: We examined 2 employment outcomes from 2003 in the Childhood Cancer Survivor Study (CCSS): (1) health-related unemployment and (2) unemployed but seeking work. We compared survivors with a nearest-age CCSS sibling cohort and examined demographic and treatment-related risk groups for each outcome. Methods: We studied 6339 survivors and 1967 siblings ≥25 years of age excluding those unemployed by choice. Multivariable generalized linear models evaluated whether survivors were more likely to be unemployed than siblings and whether certain survivors were at a higher risk for unemployment. Results: Survivors (10.4%) reported health-related unemployment more often than siblings (1.8%; Relative Risk [RR], 6.07; 95% Confidence Interval [CI], 4.32-8.53). Survivors (5.7%) were more likely to report being unemployed but seeking work than siblings (2.7%; RR, 1.90; 95% CI, 1.43-2.54). Health-related unemployment was more common in female survivors than males (Odds Ratio [OR], 1.73; 95% CI, 1.43-2.08). Cranial radiotherapy doses ≥25 Gy were associated with higher odds of unemployment (health-related: OR, 3.47; 95% CI, 2.54-4.74; seeking work: OR, 1.77; 95% CI, 1.15-2.71). Unemployed survivors reported higher levels of poor physical functioning than employed survivors, and had lower education and income and were more likely to be publicly insured than unemployed siblings. Conclusions: Childhood cancer survivors have higher levels of unemployment because of health or being between jobs. High-risk survivors may need vocational assistance. © 2010 by Lippincott Williams & Wilkins.
Keywords: adult; controlled study; disease-free survival; middle aged; leukemia; major clinical study; united states; cancer radiotherapy; radiation dose; neoplasms; linear models; demography; quality of life; cohort analysis; odds ratio; risk factors; attitude to health; risk factor; central nervous system tumor; childhood cancer; hodgkin disease; cancer survivor; siblings; survivors; confidence intervals; nonhodgkin lymphoma; health status; neuroblastoma; education; soft tissue sarcoma; physical activity; health; high risk population; sibling; kidney cancer; employment status; mental health; socioeconomics; socioeconomic factors; income; bone cancer; pediatric cancer; employment; cancer survivorship; unemployment; vocation
Journal Title: Medical Care
Volume: 48
Issue: 11
ISSN: 0025-7079
Publisher: Lippincott Williams & Wilkins  
Date Published: 2010-11-01
Start Page: 1015
End Page: 1025
Language: English
DOI: 10.1097/MLR.0b013e3181eaf880
PUBMED: 20940653
PROVIDER: scopus
PMCID: PMC3428202
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: MDLCB" - "Source: Scopus"
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  1. Kevin Oeffinger
    296 Oeffinger