Cell fate plug and play: Direct reprogramming and induced pluripotency Journal Article
| Authors: | Chambers, S. M.; Studer, L. |
| Article Title: | Cell fate plug and play: Direct reprogramming and induced pluripotency |
| Abstract: | Building on the discovery that MyoD expression reprograms fibroblasts into muscle, three papers (Vierbuchen et al.; 2010; Ieda et al.; 2010; Szabo et al.; 2010) recently reported the reprogramming of fibroblasts into neurons, cardiomyocytes, and blood cell progenitors without first passing the cells through a pluripotent state. Here we discuss the advantages and challenges of harnessing this direct reprogramming method for regenerative medicine. © 2011 Elsevier Inc. All Rights Reserved. |
| Keywords: | review; nonhuman; transcription factor; cell fate; cell type; fibroblast; pluripotent stem cell; nuclear reprogramming; regenerative medicine |
| Journal Title: | Cell |
| Volume: | 145 |
| Issue: | 6 |
| ISSN: | 0092-8674 |
| Publisher: | Cell Press |
| Date Published: | 2011-06-10 |
| Start Page: | 827 |
| End Page: | 830 |
| Language: | English |
| DOI: | 10.1016/j.cell.2011.05.036 |
| PROVIDER: | scopus |
| PUBMED: | 21663788 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 17 August 2011" - "CODEN: CELLB" - "Source: Scopus" |
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