Authors: | Charles, N. A.; Holland, E. C. |
Article Title: | TRRAP and the maintenance of stemness in gliomas |
Abstract: | Resistance of brain tumors to therapy and their eventual recurrence is attributed to stem-like cells. In this issue of Cell Stem Cell, a high-throughput kinome-wide screen (Wurdak et al., 2010) has identified TRRAP, a kinase-related protein, as being required for stem cell character in gliomas. © 2010 Elsevier Inc. All rights reserved. |
Keywords: | signal transduction; protein expression; unclassified drug; nonhuman; cancer radiotherapy; glioma; protein function; cell proliferation; protein analysis; phenotype; cell function; protein depletion; cell differentiation; carcinogenesis; cancer inhibition; cancer stem cell; short survey; drug sensitivity; adaptor protein; cyclin a2; transformation transcription domain associated protein |
Journal Title: | Cell Stem Cell |
Volume: | 6 |
Issue: | 1 |
ISSN: | 1934-5909 |
Publisher: | Cell Press |
Date Published: | 2010-01-08 |
Start Page: | 6 |
End Page: | 7 |
Language: | English |
DOI: | 10.1016/j.stem.2009.12.005 |
PROVIDER: | scopus |
PUBMED: | 20085736 |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 20 April 2011" - "Source: Scopus" |