TRRAP and the maintenance of stemness in gliomas Journal Article


Authors: Charles, N. A.; Holland, E. C.
Article Title: TRRAP and the maintenance of stemness in gliomas
Abstract: Resistance of brain tumors to therapy and their eventual recurrence is attributed to stem-like cells. In this issue of Cell Stem Cell, a high-throughput kinome-wide screen (Wurdak et al., 2010) has identified TRRAP, a kinase-related protein, as being required for stem cell character in gliomas. © 2010 Elsevier Inc. All rights reserved.
Keywords: signal transduction; protein expression; unclassified drug; nonhuman; cancer radiotherapy; glioma; protein function; cell proliferation; protein analysis; phenotype; cell function; protein depletion; cell differentiation; carcinogenesis; cancer inhibition; cancer stem cell; short survey; drug sensitivity; adaptor protein; cyclin a2; transformation transcription domain associated protein
Journal Title: Cell Stem Cell
Volume: 6
Issue: 1
ISSN: 1934-5909
Publisher: Cell Press  
Date Published: 2010-01-08
Start Page: 6
End Page: 7
Language: English
DOI: 10.1016/j.stem.2009.12.005
PROVIDER: scopus
PUBMED: 20085736
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 20 April 2011" - "Source: Scopus"
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  1. Eric Holland
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  2. Nikki Charles
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