Current advances in targeted therapies for metastatic gastric cancer: Improving patient care Journal Article
| Authors: | Aguiar, P. N.; Pimentel Muniz, T.; Rodrigues Miranda, R.; Tadokoro, H.; Forones, N. M.; Monteiro, I. D. P.; Castelo-Branco, P.; Janjigian, Y. Y.; De Mello, R. A. |
| Article Title: | Current advances in targeted therapies for metastatic gastric cancer: Improving patient care |
| Abstract: | In this article, we review the literature on the current advances in targeted therapies for metastatic gastric cancer aimed at improving patient care. We conclude that the key to guiding targeted therapy is individual biomarkers, which are not completely elucidated. HER2 overexpression is the only predictive biomarker currently in use. Furthermore, it is necessary to understand that gastric tumors are heterogeneous; therefore, is impossible to evaluate a novel biological compound without evaluating personal biomarkers. The selection of patients who are able to receive each treatment is paramount for improving advanced gastric cancer survival and reducing unnecessary costs. © 2016 Future Medicine Ltd. |
| Keywords: | patient care; targeted therapy; gastric cancer; current advances; gastric cancer therapy |
| Journal Title: | Future Oncology |
| Volume: | 12 |
| Issue: | 6 |
| ISSN: | 1479-6694 |
| Publisher: | Future Medicine |
| Date Published: | 2016-01-01 |
| Start Page: | 839 |
| End Page: | 854 |
| Language: | English |
| DOI: | 10.2217/fon.15.348 |
| PROVIDER: | scopus |
| PUBMED: | 26838766 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 4 April 2016 -- Source: Scopus |
