Critical evaluation of the World Health Organization classification of myelodysplasia and acute myeloid leukemia Journal Article


Authors: Heaney, M. L.; Golde, D. W.
Article Title: Critical evaluation of the World Health Organization classification of myelodysplasia and acute myeloid leukemia
Abstract: The separation of myelodysplastic syndromes from acute myeloid leukemia has been problematic because, as clinical entities, they represent different points in the spectrum of the same disease process. A new classification by the World Health Organization has incorporated recent prognostic findings in myelodysplastic syndrome and distinct genetic subtypes of acute myelogenous leukemia to provide an improved conceptual framework, if not a simpler nomenclature. Here, we review the new classification system and discuss its impact on diagnosis and treatment.
Keywords: acute granulocytic leukemia; review; united states; sensitivity and specificity; classification; myelodysplastic syndrome; evaluation; world health organization; nomenclature; myelodysplastic syndromes; terminology; leukemia, myelocytic, acute; humans; human
Journal Title: Current Oncology Reports
Volume: 2
Issue: 2
ISSN: 1523-3790
Publisher: Springer  
Date Published: 2000-04-01
Start Page: 140
End Page: 143
Language: English
PUBMED: 11122835
PROVIDER: scopus
DOI: 10.1007/s11912-000-0085-x
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Mark L Heaney
    94 Heaney
  2. David Golde
    127 Golde