Giant hepatic hemangioma with Kasabach-Merritt syndrome: Is the appropriate treatment enucleation of liver transplantation? Journal Article


Authors: Hochwald, S. N.; Blumgart, L. H.
Article Title: Giant hepatic hemangioma with Kasabach-Merritt syndrome: Is the appropriate treatment enucleation of liver transplantation?
Abstract: We present a case of giant cavernous hemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by enucleation. The 51 year old woman presented with increased abdominal girth and easy bruisability. Workup elsewhere revealed a massive hepatic hemangioma and she was started on radiation therapy to the lesion and offered an orthotopic liver transplant. After careful preoperative preparation, we felt that resection was possible and she underwent a successful enucleation. The operation and postoperative course were complicated by bleeding but she recovered and remains well in followup after 6 months. All coagulation parameters have returned to normal. Enucleation should be considered the treatment of choice for hepatic hemangiomas, including those presenting with Kasabach-Merritt syndrome. The benefits of enucleation as compared to liver transplantation for these lesions are discussed.
Keywords: adult; treatment outcome; middle aged; case report; liver transplantation; liver neoplasms; cancer radiotherapy; preoperative care; follow up; liver; intermethod comparison; enucleation; postoperative hemorrhage; liver hemangioma; hemangioma; disseminated intravascular coagulation; disseminated intravascular clotting; hemangioma, cavernous; humans; human; female; priority journal; article; blood clotting parameters; kasabach-merritt syndrome; kasabach merritt syndrome
Journal Title: HPB Surgery
Volume: 11
Issue: 6
ISSN: 0894-8569
Publisher: Hindawi Publishing Corporation  
Date Published: 2000-01-01
Start Page: 413
End Page: 419
Language: English
PUBMED: 10977121
PROVIDER: scopus
PMCID: PMC2424000
DOI: 10.1155/2000/25954
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Leslie H Blumgart
    352 Blumgart