A 33-year-old woman with jaundice after azithromycin use Journal Article


Authors: Suriawinata, A.; Min, A. D.
Article Title: A 33-year-old woman with jaundice after azithromycin use
Abstract: A 33-year-old woman presented with jaundice and pruritus. She had taken a 5-day course of azithromycin followed by one day of erythromycin for a flu-like syndrome. She was previously healthy with no history of hepatitis virus exposure or other liver-related diseases. Total bilirubin, serum transaminases, and alkaline phosphatase were highly elevated. She was diagnosed with azithromycin-induced cholestasis. Other possible causes of cholestasis were ruled out by laboratory tests and imaging studies. Liver biopsy showed changes consistent with drug-induced cholestasis. She was treated with cholestyramine and underwent six courses of plasmapheresis. Two months later, her total bilirubin and serum transaminases were back to normal. The patient maintained entirely normal biochemical liver tests at her 4-year follow-up visit.
Keywords: adult; disease course; histopathology; case report; differential diagnosis; steroid; plasmapheresis; drug effect; biopsy; pruritus; anti-bacterial agents; jaundice; flu like syndrome; azithromycin; liver biopsy; oral contraceptive agent; cholestasis; erythromycin; propranolol; anticholesteremic agents; cholestatic hepatitis; humans; human; female; priority journal; article; sumatriptan; hepatitis, toxic; colestyramine; cholestyramine
Journal Title: Seminars in Liver Disease
Volume: 22
Issue: 2
ISSN: 0272-8087
Publisher: Thieme Publishing  
Date Published: 2002-01-01
Start Page: 207
End Page: 210
Language: English
DOI: 10.1055/s-2002-30107
PUBMED: 12016551
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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