Developments in nuclear magnetic resonance imaging and spectroscopy: Application to radiation oncology Journal Article


Authors: Zakian, K. L.; Koutcher, J. A.; Ballon, D.; Hricak, H.; Ling, C. C.
Article Title: Developments in nuclear magnetic resonance imaging and spectroscopy: Application to radiation oncology
Abstract: Nuclear magnetic resonance techniques have advanced to the point where functional, physiologic, and biochemical information may be obtained from patients. Magnetic resonance imaging of tissue water can be used to measure perfusion and diffusion with submillimeter resolution. Magnetic resonance spectroscopy may be applied to the assessment of tissue metabolites that contain protons, phosphorus, fluorine, or other nuclei. The combination of imaging and spectroscopy technologies has lead to spectroscopic imaging techniques that are capable of mapping proton metabolites at resolutions as small as 0.25 cm3 within the time constraints of a clinical imaging study. This article provides a brief review of magnetic resonance techniques for imaging of tissue physiological function and addresses possible applications in the realm of radiation oncology. © 2001 by W.B. Saunders Company.
Keywords: review; nonhuman; nuclear magnetic resonance imaging; magnetic resonance imaging; neoplasms; animals; diffusion; diagnostic imaging; oncology; physiology; diagnostic value; neoplasms, experimental; magnetic resonance spectroscopy; intermethod comparison; biochemistry; spectroscopy; metabolite; proton transport; proton; phosphorus; tissue perfusion; fluorine; drug disposition; cancer; humans; human; priority journal; tissue water
Journal Title: Seminars in Radiation Oncology
Volume: 11
Issue: 1
ISSN: 1053-4296
Publisher: Elsevier Inc.  
Date Published: 2001-01-01
Start Page: 3
End Page: 15
Language: English
PUBMED: 11146038
PROVIDER: scopus
DOI: 10.1053/srao.2001.18099
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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MSK Authors
  1. Douglas J Ballon
    36 Ballon
  2. Hedvig Hricak
    340 Hricak
  3. Kristen L Zakian
    77 Zakian
  4. Jason A Koutcher
    241 Koutcher
  5. C Clifton Ling
    323 Ling