Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma Journal Article


Authors: Kanamori, M.; Antonescu, C. R.; Scott, M.; Bridge, R. S.; Neff, J. R.; Spanier, S. S.; Scarborough, M. T.; Vergara, G.; Rosenthal, H. G.; Bridge, J. A.
Article Title: Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma
Abstract: Adamantinoma of long bones is a rare neoplasm predominantly involving the tibia Cytogenetic studies of adamantinoma are few. Cytogenetic or molecular cytogenetic analysis of four adamantinomas, and a review of eleven cases in the literature reveals extra copies of chromosomes 7, 8, 12, 19, and 21 as recurrent in this neoplasm. Adamantinoma may be confused with a variety of primary and metastatic epithelial and mesenchymal neoplasms. Observation of these aneuploidies may be useful in establishing the diagnosis of adamantinoma.
Keywords: long bones; osteofibrous dysplasia
Journal Title: Journal of Molecular Diagnostics
Volume: 3
Issue: 1
ISSN: 1525-1578
Publisher: Elsevier Science, Inc.  
Date Published: 2001-02-01
Start Page: 16
End Page: 21
Language: English
ACCESSION: WOS:000166920000003
DOI: 10.1016/s1525-1578(10)60644-7
PROVIDER: wos
PMCID: PMC1907347
PUBMED: 11227067
Notes: Article -- Source: Wos
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  1. Cristina R Antonescu
    895 Antonescu