Proceedings of the North American Society of Head and Neck Pathology, Los Angeles, CA, March 20, 2022. Emerging bone and soft tissue neoplasms in the head and neck region Conference Paper
| Author: | Xu, B. |
| Title: | Proceedings of the North American Society of Head and Neck Pathology, Los Angeles, CA, March 20, 2022. Emerging bone and soft tissue neoplasms in the head and neck region |
| Conference Title: | 2022 North American Society Of Head And Neck Pathology Companion Meeting |
| Abstract: | In the past decade, several emerging bone and soft tissue neoplasms of the head and neck region have been described in the literature, including GLI1-altered mesenchymal tumors, (intraosseous) rhabdomyosarcoma with TFCP2 fusion, and adamantinoma-like Ewing sarcoma. This review provides a summary of the clinical features, histologic characteristics, immunoprofile, key diagnostic features, and differential diagnoses of these emerging entities. Notably, all three entities show epithelioid morphology and cytokeratin immunopositivity, highlighting the need to consider these mesenchymal neoplasms in the differential diagnoses of cytokeratin-positive epithelioid tumors in the head and neck region. Appropriate workups including detection of the characteristic molecular alterations are essential for the correct diagnosis. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
| Keywords: | bone neoplasms; bone tumor; dna binding protein; dna-binding proteins; transcription factor; pathology; tumor marker; transcription factors; ewing sarcoma; head and neck neoplasms; keratins; soft tissue neoplasms; soft tissue tumor; head and neck tumor; keratin; california; los angeles; sarcoma, ewing; humans; human; adamantinoma-like ewing sarcoma; biomarkers, tumor; ectomesenchymal chondromyxoid tumor; gli1-altered mesenchymal tumor; rhabdomyosarcoma with tfcp2 rearrangement; spindle/sclerosing rhabdomyosarcoma; tfcp2 protein, human |
| Journal Title | Head and Neck Pathology |
| Volume: | 16 |
| Issue: | 1 |
| Conference Dates: | 2022 Mar 20 |
| Conference Location: | Los Angeles, CA |
| ISBN: | 1936-055X |
| Publisher: | Humana Press Inc |
| Date Published: | 2022-03-01 |
| Start Page: | 158 |
| End Page: | 167 |
| Language: | English |
| DOI: | 10.1007/s12105-022-01418-9 |
| PUBMED: | 35307771 |
| PROVIDER: | scopus |
| PMCID: | PMC9019004 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 August 2022 -- Source: Scopus |
