Role of cytotoxic therapy with hematopoietic cell transplantation in the treatment of Hodgkin lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation Journal Article

  


Authors: Perales, M. A.; Ceberio, I.; Armand, P.; Burns, L. J.; Chen, R.; Cole, P. D.; Evens, A. M.; Laport, G. G.; Moskowitz, C. H.; Popat, U.; Reddy, N. M.; Shea, T. C.; Vose, J. M.; Schriber, J.; Savani, B. N.; Carpenter, P. A.
Article Title: Role of cytotoxic therapy with hematopoietic cell transplantation in the treatment of Hodgkin lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation
Abstract: The role of hematopoietic cell transplantation (HCT) in the therapy of Hodgkin lymphoma (HL) in pediatric and adult patients is reviewed and critically evaluated in this systematic evidence-based review. Specific criteria were used for searching the published literature and for grading the quality and strength of the evidence and the strength of the treatment recommendations. Treatment recommendations based on the evidence are included and were reached unanimously by a panel of HL experts. Both autologous and allogeneic HCT offer a survival benefit in selected patients with advanced or relapsed HL and are currently part of standard clinical care. Relapse remains a significant cause of failure after both transplant approaches, and strategies to decrease the risk of relapse remain an important area of investigation. (C) 2015 American Society for Blood and Marrow Transplantation.
Keywords: oncology; long-term survivors; hodgkin lymphoma; positron-emission-tomography; national-cancer-institute; progression-free survival; combined-modality therapy; bone-marrow; transplant; acute; lymphoblastic-leukemia; hematopoietic cell transplantation; allogeneic transplant; high-dose chemotherapy; autologous; group-report; intensity allogeneic transplantation
Journal Title: Biology of Blood and Marrow Transplantation
Volume: 21
Issue: 6
ISSN: 1083-8791
Publisher: Elsevier Inc.  
Date Published: 2015-06-01
Start Page: 971
End Page: 983
Language: English
ACCESSION: WOS:000354667900003
DOI: 10.1016/j.bbmt.2015.02.022
PROVIDER: wos
PUBMED: 25773017
Notes: Article -- Source: Wos
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MSK Authors
  1. Craig Moskowitz
    407 Moskowitz
  2. Miguel-Angel Perales
    918 Perales
  3. Izaskun Ceberio
    10 Ceberio
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