Hematopoietic stem cell transplantation for multiple myeloma: Guidelines from the American Society for Blood and Marrow Transplantation Journal Article

  


Authors: Shah, N.; Callander, N.; Ganguly, S.; Gul, Z.; Hamadani, M.; Costa, L.; Sengsayadeth, S.; Abidi, M.; Hari, P.; Mohty, M.; Chen, Y. B.; Koreth, J.; Landau, H.; Lazarus, H.; Leather, H.; Majhail, N.; Nath, R.; Osman, K.; Perales, M. A.; Schriber, J.; Shaughnessy, P.; Vesole, D.; Vij, R.; Wingard, J.; Giralt, S.; Savani, B. N.
Article Title: Hematopoietic stem cell transplantation for multiple myeloma: Guidelines from the American Society for Blood and Marrow Transplantation
Abstract: Therapeutic strategies for multiple myeloma (MM) have changed dramatically over the past decade. Thus, the role of hematopoietic stem cell transplantation (HCT) must be considered in the context of this evolution. In this evidence-based review, we have critically analyzed the data from the most recent clinical trials to better understand how to incorporate HCT and when HCT is indicated. We have provided our recommendations based on strength of evidence with the knowledge that ongoing clinical trials make this a dynamic field. Within this document, we discuss the decision to proceed with autologous HCT, factors to consider before proceeding to HCT, the role of tandem autologous HCT, post-HCT maintenance therapy, and the role of allogeneic HCT for patients with MM. © 2015 American Society for Blood and Marrow Transplantation.
Keywords: cancer chemotherapy; event free survival; treatment response; disease course; review; cancer recurrence; salvage therapy; follow up; antineoplastic agent; quality of life; multiple myeloma; maintenance therapy; cytogenetics; practice guideline; hematopoietic stem cell transplantation; transplantation; age; cancer regression; therapy delay; comorbidity; long term care; medical society; allogeneic hematopoietic stem cell transplantation; intermethod comparison; guidelines; autologous hematopoietic stem cell transplantation; recommendations; clinical trial (topic); human
Journal Title: Biology of Blood and Marrow Transplantation
Volume: 21
Issue: 7
ISSN: 1083-8791
Publisher: Elsevier Inc.  
Date Published: 2015-07-01
Start Page: 1155
End Page: 1166
Language: English
DOI: 10.1016/j.bbmt.2015.03.002
PROVIDER: scopus
PUBMED: 25769794
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84930577739&partnerID=40&md5=24a612e27de104b6b8d238b5acc37fcc
Notes: Export Date: 2 July 2015 -- Source: Scopus
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  2. Miguel-Angel Perales
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  3. Heather Jolie Landau
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