Intravenous injection of indocyanine green results in an artificial transient desaturation by pulse oximetry Journal Article
| Authors: | Ediriwickrema, L. S.; Francis, J. H.; Arslan Carlon, V.; Dalecki, P. H.; Brodie, S. E.; Marr, B. P.; Abramson, D. H. |
| Article Title: | Intravenous injection of indocyanine green results in an artificial transient desaturation by pulse oximetry |
| Abstract: | Purpose: To describe a case series of transient oxygen desaturation measured by pulse oximetry during the intravenous infusion of indocyanine green to enhance transpupillary thermotherapy in treating retinoblastoma after ophthalmic artery chemosurgery. Methods: Retrospective descriptive case series. Results: The intravenous administration of indocyanine green for ophthalmic angiography resulted in a transient drop in oxygen saturation as measured by Nellcor fingertip pulse oximetry in three children with retinoblastoma receiving indocyanine green-guided transpupillary thermotherapy. The magnitude of reduction ranged from 92% to 94% from an initial reading of 99% to 100% in each case, with an average duration of 3 minutes. Concurrent measurement of blood pressure, pulse, and expired CO2 showed no changes during this process. Conclusion: Administration of intravenous indocyanine green resulted in a transient desaturation by oximetry during transpupillary thermotherapy for children with retinoblastoma under anesthesia because of the fluorescent dye's absorption of red light in a manner similar to that of deoxygenated hemoglobin, thereby leading to transient instrument misinterpretation and miscalculation of arterial oxygenation. © 2015 by Ophthalmic Communications Society, Inc. |
| Keywords: | child; preschool child; case report; unspecified side effect; oxygen; retinoblastoma; retrospective study; chemosurgery; blood pressure measurement; pulse rate; case study; descriptive research; pulse oximetry; desaturation; indocyanine green; diode laser; transpupillary thermotherapy; human; male; female; article; indocyanine green angiography; oxygen desaturation |
| Journal Title: | Retinal Cases and Brief Reports |
| Volume: | 9 |
| Issue: | 3 |
| ISSN: | 1935-1089 |
| Publisher: | Ophthalmic Communications Society, Inc |
| Date Published: | 2015-01-01 |
| Start Page: | 252 |
| End Page: | 255 |
| Language: | English |
| DOI: | 10.1097/icb.0000000000000152 |
| PROVIDER: | scopus |
| PUBMED: | 26002141 |
| DOI/URL: | |
| Notes: | Export Date: 2 July 2015 -- Source: Scopus |
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