Indocyanine green enhanced transpupillary thermotherapy in combination with ophthalmic artery chemosurgery for retinoblastoma Journal Article

  

Authors:	Francis, J. H.; Abramson, D. H.; Brodie, S. E.; Marr, B. P.
Article Title:	Indocyanine green enhanced transpupillary thermotherapy in combination with ophthalmic artery chemosurgery for retinoblastoma
Abstract:	Purpose: Review our experience in the use of indocyanine green (ICG) enhanced transpupillary thermotherapy (TTT) in combination with ophthalmic artery chemosurgery for retinoblastomas unresponsive to standard TTT. Methods: Single centre, retrospective study of 16 eyes in 13 retinoblastoma patients treated with TTT and ICG via indirect ophthalmoscope: 23 treatments of 16 eyes, with a mean follow-up of 12.1 months (range 3-35 months). Outcome measures included tumour response and electroretinogram. Results: Treatment resulted in significant tumour regression in all eyes: 13 eyes with well-differentiated characteristics, 2 with implanting vitreous seeds and 1 eye refractory to traditional TTT. ERG function was retained in all eyes. Conclusions: ICG-enhanced TTT with ophthalmic artery chemosurgery can effectively treat retinoblastoma refractory to conventional focal treatments without deleterious ocular side effects. © Br J Ophthalmol 2013.
Keywords:	child; clinical article; preschool child; review; follow up; retinoblastoma; tumor regression; retrospective study; infant; ophthalmic artery; chemosurgery; electroretinogram; indocyanine green; diode laser; ophthalmoscope; transpupillary thermotherapy
Journal Title:	British Journal of Ophthalmology
Volume:	97
Issue:	2
ISSN:	0007-1161
Publisher:	BMJ Publishing Group Ltd.
Date Published:	2013-02-01
Start Page:	164
End Page:	168
Language:	English
DOI:	10.1136/bjophthalmol-2012-302495
PROVIDER:	scopus
PUBMED:	23143908
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84872927533&partnerID=40&md5=5759a057ad32229a912449600db4e044
Notes:	--- - "Export Date: 1 March 2013" - "CODEN: BJOPA" - "Source: Scopus"

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